The Brain Stimulation Journal:
Basic, Translational, and Clinical Research in Neuromodulation Feed. This feed contains the latest published articles, both articles that have been published in an issue as well as articles that have been published as Articles in Press.
- Transcranial Direct Current Stimulation Facilitates Insight LearningAfter two decades of transcranial direct current stimulation (tDCS) research, it is still unclear which applications benefit most from which tDCS protocols. One prospect is the acceleration of learning, where previous work has demonstrated that anodal tDCS applied to the right ventrolateral prefrontal cortex (rVLPFC) is capable of doubling the rate of learning in a visual camouflaged target detection and classification task. ... read more3 weeks ago
- Transcranial Direct Current Stimulation for a Patient with Locked-in SyndromeLocked-in syndrome (LIS) was first introduced by Plum and Posner. It refers to the combination of quadriplegia and anarthria brought about by disruption of the corticospinal and corticobulbar pathways of the brain stem, respectively [1]. Patients with LIS are alert and aware of their environment but cannot speak or move their limbs. They retain the capacity to use vertical eye movements and blinking to communicate. LIS occurs following disruption of the motor tracts in the ventral brain stem and at least 60% of the cases are caused by stroke [2].Early and intensive rehabilitation reportedly improves the functional outcome and reduces ... read more4 weeks ago
- Matching stimulation paradigms resolve apparent differences between optogenetic and electrical VTA stimulationOptogenetic stimulation has grown into a popular brain stimulation method in basic neuroscience while electrical stimulation predominates in clinical applications. In order to explain the effects of electrical stimulation on a cellular level and evaluate potential advantages of optogenetic therapies, comparisons between the two stimulation modalities are necessary. This comparison is hindered, however, by the difficulty of effectively matching the two fundamentally different modalities. ... read more1 month ago
- Effects of bilateral anodal transcranial direct current stimulation over the tongue primary motor cortex on cortical excitability of the tongue and tongue motor functionsTranscranial direct current stimulation (tDCS) is a non-invasive tool for inducing cortical excitability changes [1]. Numerous studies have investigated the effects of tDCS over the primary motor cortex (M1) for exploring mechanisms underlying cortical plasticity and motor functions of the limbs. However, little is known about the effects of tDCS on the tongue region. Here, we investigated the effects of anodal tDCS over the bilateral tongue M1 representation relative to those of unilateral anodal tDCS on tongue region cortical excitability and tongue and jaw motor functions. ... read more2 months ago
- Cerebellar repetitive transcranial magnetic stimulation (rTMS) for essential tremor: A double-blind, sham-controlled, crossover, add-on clinical trialThere is controversial evidence about the effect of cerebellar low-frequency stimulation in patients with essential tremor (ET). ... read more2 months ago
- A case series exploring the effect of twenty sessions of repetitive transcranial magnetic stimulation (rTMS) on cannabis use and cravingCurrently there are few evidence based treatments for Cannabis Use Disorder (CUD), and those that are available have limited efficacy [1]. Cannabis craving is a commonly described behavioral construct in CUD [2], and may have clinical relevance. An expanding evidence base suggests that repetitive transcranial magnetic stimulation (rTMS) applied to the dorsolateral prefrontal cortex (DLPFC) decreases craving across a variety of different substance use disorders and may have treatment efficacy [3]. ... read more3 months ago
- Probing the circuitry of panic with deep brain stimulation: Connectomic analysis and review of the literaturePanic attacks affect a sizeable proportion of the population. The neurocircuitry of panic remains incompletely understood. ... read more3 months ago
- Transcranial direct current stimulation (tDCS) for the treatment of a Multiple Sclerosis symptom clusterPeople with Multiple Sclerosis (PwMS) have an over five-fold increased risk of experiencing and being treated for neuropathic pain. Interestingly, pain has been described as a potentially moderating factor of fatigue and depression [1]. Up to 92% of PwMS are affected by fatigue [2] and 24% suffer from depression [3]. Depressed PwMS are more likely to have pain and there is a positive association between the interference of painful symptoms, and pain severity, with depression severity [4]. Pain, fatigue, and depression are interdependently associated and potentially modifiable [5]. ... read more3 months ago
- Transcranial direct current stimulation reduces seizure frequency in patients with refractory focal epilepsy: A randomized, double-blind, sham-controlled, and three-arm parallel multicenter studyTranscranial direct current stimulation (tDCS) has been explored in epilepsy with limited samples, varied parameters, and inconclusive results. We aimed to study the efficacy of tDCS for patients with refractory focal epilepsy. ... read more3 months ago
- Feasibility of home-based, self-applied transcranial direct current stimulation to enhance motor learning in middle-aged and older adultsWe read with great interest the recent letter sent to you by McConnell and colleagues [1], in which they discuss one of the first applications of truly independent home-based electrical brain stimulation, applied following safety recommendations. Transcranial direct-current stimulation (tDCS) is a non-invasive brain stimulation technique capable of modulating cortical excitability beyond the stimulation period [2,3]. tDCS presents interesting options as a therapeutic intervention in multiple neurological disorders, such as stroke, depression, chronic pain, schizophrenia, and Alzheimer's and Parkinson's diseases [4,5]. ... read more3 months ago