High-definition transcranial direct current stimulation modulates theta response during a Go-NoGo task in traumatic brain injury

High-definition transcranial direct current stimulation modulates theta response during a Go-NoGo task in traumatic brain injury
Clin Neurophysiol. 2022 Aug 30;143:36-47. doi: 10.1016/j.clinph.2022.08.015. Online ahead of print.ABSTRACTOBJECTIVE: High Definition transcranial Direct Current Stimulation (HD-tDCS) has been shown to improve cognitive performance in individuals with chronic traumatic brain injury (TBI), although electrophysiological mechanisms remain unclear.METHODS: Veterans with TBI underwent active anodal (N = 15) vs sham (N = 10) HD-tDCS targeting the pre-supplementary motor area (pre-SMA). A Go-NoGo task was conducted simultaneously with electroencephalography (EEG) at baseline and after intervention completion.RESULTS: We found increased theta event-related spectral perturbation (ERSP) and inter-trial phase coherence (ITPC) during Go in the frontal midline electrodes overlying the pre-SMA after active HD-tDCS ... read more
Pubmed – tDCS and CognitionBy Hsueh-Sheng Chiang