Nicotine modulates human brain plasticity via calcium-dependent mechanisms.

Nicotine modulates human brain plasticity via calcium-dependent mechanisms.
Related ArticlesNicotine modulates human brain plasticity via calcium-dependent mechanisms. J Physiol. 2018 Sep 15;: Authors: Jessica G, Jerick B, Giorgi B, Min-Fang K, Walter P, Michael N Abstract KEY POINT: Nicotine modulates cognition and memory function by targeting the nicotinic acetylcholine receptor and releasing different transmitter systems postsynaptically. With both nicotine-generated mechanisms, calcium influx and calcium permeability can be regulated, which is a key requirement for the induction of long-term potentiation, the physiological basis of learning and memory function. We try to unmask the underlying mechanism of nicotinic effects on anodal tDCS-induced LTP-like plasticity based on the hypothesis of calcium-dependency. ... read more
Pubmed – tDCS and Cognition