Novel tools for rapid online data acquisition of the TMS stimulus-response curve

Novel tools for rapid online data acquisition of the TMS stimulus-response curve
A change in the input-output relationship between transcranial magnetic stimulation (TMS) and the motor evoked potential (MEP) may be used as a marker for neuroplasticity [1–3]. Traditionally, stimulus response (SR) curve data are acquired using 3–10 stimulation intensity bins determined a priori as a percentage of the resting or active motor threshold, with 5–20 stimuli/bin and interstimulus intervals (ISI) ranging from 3 to 10 s. Data acquisition often exceeds 10 min, and therefore curves can susceptible to changes in corticospinal excitability as a result of attention, drowsiness and emotional state [4–7]. ... read more
Brain Stimulation Journal FeedBy Mark van de Ruit, Tom Pearson, Michael J. Grey