Repetitive transcranial magnetic stimulation of the left dorsolateral prefrontal cortex may improve symptoms of anhedonia in individuals with cocaine use disorder: A pilot study

Repetitive transcranial magnetic stimulation of the left dorsolateral prefrontal cortex may improve symptoms of anhedonia in individuals with cocaine use disorder: A pilot study
Cocaine use disorder (CUD) is characterized by positive symptoms, such as craving, and negative affective states, all of which may drive drug taking and relapse. One prominent symptom that is part of the negative affective states is termed anhedonia, and is defined as an impaired ability to experience pleasure from natural rewards such as food, water, sex, and nurturing. From a neurobiological standpoint, disruption in dopaminergic mesocorticolimbic reward processing plays an important role in the development of anhedonia [1]. ... read more
Brain Stimulation Journal FeedBy Mauro Pettorruso, Primavera Alessandra Spagnolo, Lorenzo Leggio, Luigi Janiri, Massimo Di Giannantonio, Luigi Gallimberti, Antonello Bonci, Giovanni Martinotti