PubMed Transcranial Direct Current Stimulation

  • Anodal transcranial direct current stimulation affects auditory cortex plasticity in normal-hearing and noise-exposed rats.
    Related ArticlesAnodal transcranial direct current stimulation affects auditory cortex plasticity in normal-hearing and noise-exposed rats. Brain Stimul. 2018 May 31;: Authors: Paciello F, Podda MV, Rolesi R, Cocco S, Petrosini L, Troiani D, Fetoni AR, Paludetti G, Grassi C Abstract BACKGROUND: Transcranial direct current stimulation (tDCS) is a non-invasive tool capable to modulate cortical functions by affecting neuronal excitability and synaptic plasticity. OBJECTIVE: Here we investigated the effects of anodal tDCS on auditory cortex (ACx) in normal-hearing rats and following a paradigm of noise-induced hearing loss (NIHL), that causes morphological alterations in ACx pyramidal neurons. METHODS: Male rats exposed to ... read more
    PubMed Transcranial Direct Current Stimulation
  • Augmentation of Fear Extinction by Transcranial Direct Current Stimulation (tDCS).
    Related ArticlesAugmentation of Fear Extinction by Transcranial Direct Current Stimulation (tDCS). Front Behav Neurosci. 2018;12:76 Authors: Dittert N, Hüttner S, Polak T, Herrmann MJ Abstract Although posttraumatic stress disorder (PTSD; DSM-V 309.82) and anxiety disorders (DSM-V 300.xx) are widely spread mental disorders, the effectiveness of their therapy is still unsatisfying. Non-invasive brain-stimulation techniques like transcranial direct current stimulation (tDCS) might be an option to improve extinction learning, which is a main functional factor of exposure-based therapy for anxiety disorders. To examine this hypothesis, we used a fear conditioning paradigm with female faces as conditioned stimuli (CS) and a 95-dB female ... read more
    PubMed Transcranial Direct Current Stimulation
  • Modulation of cortical responses by transcranial direct current stimulation of dorsolateral prefrontal cortex: A resting-state EEG and TMS-EEG study.
    Related ArticlesModulation of cortical responses by transcranial direct current stimulation of dorsolateral prefrontal cortex: A resting-state EEG and TMS-EEG study. Brain Stimul. 2018 Jun 16;: Authors: Gordon PC, Zrenner C, Desideri D, Belardinelli P, Zrenner B, Brunoni AR, Ziemann U Abstract BACKGROUND: Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique with potential for cost-effective therapeutic neuromodulation. Although positive therapeutic effects were found by stimulating the dorsolateral prefrontal cortex (DLPFC), few studies have investigated physiological effects of DLPFC-tDCS. OBJECTIVES: To investigate effects of tDCS with different parameter settings applied to the left DLPFC on cortical responses, measured by ... read more
    PubMed Transcranial Direct Current Stimulation
  • The Neural Basis of and a Common Neural Circuitry in Different Types of Pro-social Behavior.
    Related ArticlesThe Neural Basis of and a Common Neural Circuitry in Different Types of Pro-social Behavior. Front Psychol. 2018;9:859 Authors: Luo J Abstract Pro-social behaviors are voluntary behaviors that benefit other people or society as a whole, such as charitable donations, cooperation, trust, altruistic punishment, and fairness. These behaviors have been widely described through non self-interest decision-making in behavioral experimental studies and are thought to be increased by social preference motives. Importantly, recent studies using a combination of neuroimaging and brain stimulation, designed to reveal the neural mechanisms of pro-social behaviors, have found that a wide range of brain areas, ... read more
    PubMed Transcranial Direct Current Stimulation
  • Transcranial direct current stimulation: A glimmer of hope for multiple sclerosis fatigue?
    Related ArticlesTranscranial direct current stimulation: A glimmer of hope for multiple sclerosis fatigue? J Clin Neurosci. 2018 Jun 15;: Authors: Ayache SS, Chalah MA Abstract Multiple sclerosis (MS) is a neurological disease of the central nervous system characterized by inflammation, demyelination and neurodegeneration. Throughout the disease process, patients may complain of a panel of sensory, motor, cognitive and behavioral symptoms. Fatigue is a debilitating manifestation of central nervous system diseases with physical, cognitive and psychosocial dimensions. In MS, fatigue could be very frequent concerning up to 90% of patients and may have a drastic impact on their quality of life. ... read more
    PubMed Transcranial Direct Current Stimulation
  • Did I Do That? Expectancy Effects of Brain Stimulation on Error-related Negativity and Sense of Agency.
    Related ArticlesDid I Do That? Expectancy Effects of Brain Stimulation on Error-related Negativity and Sense of Agency. J Cogn Neurosci. 2018 Jun 19;:1-14 Authors: Hoogeveen S, Schjoedt U, van Elk M Abstract This study examines the effects of expected transcranial stimulation on the error(-related) negativity (Ne or ERN) and the sense of agency in participants who perform a cognitive control task. Placebo transcranial direct current stimulation was used to elicit expectations of transcranially induced cognitive improvement or impairment. The improvement/impairment manipulation affected both the Ne/ERN and the sense of agency (i.e., whether participants attributed errors to oneself or the brain ... read more
    PubMed Transcranial Direct Current Stimulation
  • Current Status of Neuromodulatory Therapies for Disorders of Consciousness.
    Related ArticlesCurrent Status of Neuromodulatory Therapies for Disorders of Consciousness. Neurosci Bull. 2018 Jun 18;: Authors: Xia X, Yang Y, Guo Y, Bai Y, Dang Y, Xu R, He J Abstract Treatment for disorders of consciousness (DOCs) is still a Gordian knot. Evidence-based guidelines on the treatment of DOC patients are not currently available, while neuromodulation techniques are seen as a potential treatment. Multiple neuromodulation therapies have been applied. This article reviews the most relevant studies in the literature in order to describe a clear picture of the current state of neuromodulation therapies that could be used to treat DOC ... read more
    PubMed Transcranial Direct Current Stimulation
  • Brain Stimulation in Alzheimer’s Disease.
    Related ArticlesBrain Stimulation in Alzheimer's Disease. Front Psychiatry. 2018;9:201 Authors: Chang CH, Lane HY, Lin CH Abstract Brain stimulation techniques can modulate cognitive functions in many neuropsychiatric diseases. Pilot studies have shown promising effects of brain stimulations on Alzheimer's disease (AD). Brain stimulations can be categorized into non-invasive brain stimulation (NIBS) and invasive brain stimulation (IBS). IBS includes deep brain stimulation (DBS), and invasive vagus nerve stimulation (VNS), whereas NIBS includes transcranial magnetic stimulation (TMS), transcranial direct current stimulation (tDCS), transcranial alternating current stimulation (tACS), electroconvulsive treatment (ECT), magnetic seizure therapy (MST), cranial electrostimulation (CES), and non-invasive VNS. We reviewed ... read more
    PubMed Transcranial Direct Current Stimulation
  • Cognitive Rehabilitation in Parkinson’s Disease: Is it Feasible?
    Related ArticlesCognitive Rehabilitation in Parkinson's Disease: Is it Feasible? Arch Clin Neuropsychol. 2017 Nov 01;32(7):840-860 Authors: Biundo R, Weis L, Fiorenzato E, Antonini A Abstract Parkinson's disease (PD) is a common neurodegenerative disorder, characterized by motor and non-motor symptoms. Dementia is one of the most relevant non-motor symptoms considering its functional affect on PD patients' activities of daily living and family members' wellbeing. Cognitive abnormalities in PD are heterogeneous and reliable biomarkers to detect patients at risk for dementia early on remain to be identified. Pharmacological treatments specifically for PD dementia and mild cognitive impairment are lacking, and alternative ... read more
    PubMed Transcranial Direct Current Stimulation
  • Unilateral Application of Cathodal tDCS Reduces Transcallosal Inhibition and Improves Visual Acuity in Amblyopic Patients.
    Related ArticlesUnilateral Application of Cathodal tDCS Reduces Transcallosal Inhibition and Improves Visual Acuity in Amblyopic Patients. Front Behav Neurosci. 2018;12:109 Authors: Bocci T, Nasini F, Caleo M, Restani L, Barloscio D, Ardolino G, Priori A, Maffei L, Nardi M, Sartucci F Abstract Objective: Amblyopia is a neurodevelopmental disorder characterized by visual acuity and contrast sensitivity loss, refractory to pharmacological and optical treatments in adulthood. In animals, the corpus callosum (CC) contributes to suppression of visual responses of the amblyopic eye. To investigate the role of interhemispheric pathways in amblyopic patients, we studied the response of the visual cortex to transcranial ... read more
    PubMed Transcranial Direct Current Stimulation
  • Transcranial Direct Current Stimulation, Symptomatology, and Cognition in Psychosis: A Qualitative Review.
    Related ArticlesTranscranial Direct Current Stimulation, Symptomatology, and Cognition in Psychosis: A Qualitative Review. Front Behav Neurosci. 2018;12:94 Authors: Gupta T, Kelley NJ, Pelletier-Baldelli A, Mittal VA Abstract Schizophrenia is a chronic, debilitating condition that affects approximately 1% of the population. Individuals diagnosed with schizophrenia typically exhibit positive (e.g., hallucinations) and negative symptoms (e.g., anhedonia) and impairments in cognitive function. Given the limitations of antipsychotic medication and psychotherapy in fully treating psychosis symptomatology, there has been increasing interest in other interventions such as transcranial direct current stimulation (tDCS). tDCS is a non-invasive neuromodulation technique, that is safe, cost-effective, and widely accessible. ... read more
    PubMed Transcranial Direct Current Stimulation
  • Noninvasive stimulation.
    Related ArticlesNoninvasive stimulation. Handb Clin Neurol. 2018;155:393-405 Authors: Ferrucci R, Priori A Abstract The cerebellum plays a fundamental role in movement execution and motor control in humans. Because of multiple cerebellar connections and a broad variety of motor and nonmotor functions, the field of cerebellar stimulation with noninvasive techniques has gained success among researchers in the last few years. These techniques allow investigation of the neural network noninvasively, collecting more information on cerebellar physiology and pathophysiology. Several studies have highlighted the therapeutic potential of noninvasive brain stimulation (NIBS) - repetitive transcranial magnetic stimulation and transcranial direct current stimulation of the ... read more
    PubMed Transcranial Direct Current Stimulation
  • Plasma biomarkers in a placebo-controlled trial comparing tDCS and escitalopram efficacy in major depression.
    Plasma biomarkers in a placebo-controlled trial comparing tDCS and escitalopram efficacy in major depression. Prog Neuropsychopharmacol Biol Psychiatry. 2018 Jun 09;: Authors: Brunoni AR, Padberg F, Vieira ELM, Teixeira AL, Carvalho AF, Lotufo PA, Gattaz WF, Benseñor IM Abstract BACKGROUND: Transcranial direct current stimulation (tDCS) holds promise as a therapeutic intervention for major depressive disorder (MDD). A more precise understanding of its underlying mechanisms may aid in the identification of subsets of patients responsive to tDCS within the context of precision psychiatry. OBJECTIVE: In this ancillary investigation of the Escitalopram vs. Electrical Current Therapy for Treating Depression Clinical Study (ELECT-TDCS), ... read more
    PubMed Transcranial Direct Current Stimulation
  • Neurostimulation techniques in the treatment of cocaine dependence: A review of the literature.
    Related ArticlesNeurostimulation techniques in the treatment of cocaine dependence: A review of the literature. Addict Behav. 2018 Jan;76:145-155 Authors: Rachid F Abstract OBJECTIVE: Cocaine use disorder is a very common condition that represents a substantial public health problem, and no effective pharmacological or psychological therapies have been identified to date. Urgent therapeutic alternatives are therefore needed such as neurostimulation techniques. The purpose of this review is to describe and discuss studies that have evaluated the safety and efficacy of these techniques for the treatment of cocaine dependence. METHODS: The electronic literature on repetitive transcranial magnetic stimulation, theta-burst stimulation, deep ... read more
    PubMed Transcranial Direct Current Stimulation
  • Transcranial direct current brain stimulation decreases impulsivity in ADHD.
    Transcranial direct current brain stimulation decreases impulsivity in ADHD. Brain Stimul. 2018 Apr 23;: Authors: Allenby C, Falcone M, Bernardo L, Wileyto EP, Rostain A, Ramsay JR, Lerman C, Loughead J Abstract BACKGROUND: Impulsivity is a core deficit in attention deficit hyperactivity disorder (ADHD). Transcranial direct current stimulation (tDCS) of the dorsolateral prefrontal cortex (DLPFC) has been shown to modulate cognitive control circuits and could enhance DLPFC activity, leading to improved impulse control in ADHD. OBJECTIVE: Hypothesis: We predicted 2.0 mA anodal stimulation (tDCS) versus sham stimulation applied over the left DLPFC would improve Conners Continuous Performance Task (CPT) scores. Our ... read more
    PubMed Transcranial Direct Current Stimulation
  • The Role of Telehealth to Assist In-Home tDCS: Opportunities, Promising Results and Acceptability.
    Related ArticlesThe Role of Telehealth to Assist In-Home tDCS: Opportunities, Promising Results and Acceptability. Brain Sci. 2018 Jun 07;8(6): Authors: Hordacre B Abstract Transcranial direct current stimulation (tDCS) has shown great promise as a neuromodulatory intervention capable of improving behavioral outcomes in a range of neurological and psychiatric populations. Evidence indicates that the neuromodulatory effect of stimulation may be cumulative, with greater improvements in behavior observed following multiple treatment sessions. However, the requirement to attend clinical or research departments for multiple treatment sessions may present a barrier for many people, particularly those with greater disability or living remotely. The portability ... read more
    PubMed Transcranial Direct Current Stimulation
  • Effects of transcranial direct current stimulation on the auditory mismatch negativity response and working memory performance in schizophrenia: a pilot study.
    Related ArticlesEffects of transcranial direct current stimulation on the auditory mismatch negativity response and working memory performance in schizophrenia: a pilot study. J Neural Transm (Vienna). 2017 Nov;124(11):1489-1501 Authors: Impey D, Baddeley A, Nelson R, Labelle A, Knott V Abstract Cognitive impairment has been proposed to be the core feature of schizophrenia (Sz). Transcranial direct current stimulation (tDCS) is a non-invasive form of brain stimulation which can improve cognitive function in healthy participants and in psychiatric patients with cognitive deficits. tDCS has been shown to improve cognition and hallucination symptoms in Sz, a disorder also associated with marked sensory ... read more
    PubMed Transcranial Direct Current Stimulation
  • Using transcranial direct current stimulation to treat symptoms in mild cognitive impairment and Alzheimer’s disease.
    Related ArticlesUsing transcranial direct current stimulation to treat symptoms in mild cognitive impairment and Alzheimer's disease. Neurodegener Dis Manag. 2017 Oct;7(5):317-329 Authors: Liu CS, Rau A, Gallagher D, Rajji TK, Lanctôt KL, Herrmann N Abstract Transcranial direct current stimulation (tDCS) has recently been investigated as a potential nonpharmacological treatment for individuals with mild cognitive impairment (MCI) and Alzheimer's disease (AD). A comprehensive literature search was performed on tDCS studies published until March 2017 using MEDLINE, Embase and PsychINFO databases. 12 articles with a total of 202 MCI or AD participants were included. Although ten of the 12 studies demonstrated positive ... read more
    PubMed Transcranial Direct Current Stimulation
  • Tracking the Effect of Cathodal Transcranial Direct Current Stimulation on Cortical Excitability and Connectivity by Means of TMS-EEG.
    Related ArticlesTracking the Effect of Cathodal Transcranial Direct Current Stimulation on Cortical Excitability and Connectivity by Means of TMS-EEG. Front Neurosci. 2018;12:319 Authors: Varoli E, Pisoni A, Mattavelli GC, Vergallito A, Gallucci A, Mauro LD, Rosanova M, Bolognini N, Vallar G, Romero Lauro LJ Abstract Transcranial direct current stimulation (tDCS) is increasingly used in both research and therapeutic settings, but its precise mechanisms remain largely unknown. At a neuronal level, tDCS modulates cortical excitability by shifting the resting membrane potential in a polarity-dependent way: anodal stimulation increases the spontaneous firing rate, while cathodal decreases it. However, the neurophysiological underpinnings of ... read more
    PubMed Transcranial Direct Current Stimulation