PubMed Abstract – tDCS and memory

  • Boosting Memory by tDCS to Frontal or Parietal Brain Regions? A Study of the Enactment Effect Shows No Effects for Immediate and Delayed Recognition.
    Related ArticlesBoosting Memory by tDCS to Frontal or Parietal Brain Regions? A Study of the Enactment Effect Shows No Effects for Immediate and Delayed Recognition. Front Psychol. 2018;9:867 Authors: Meier B, Sauter P Abstract Boosting memory with transcranial direct current stimulation (tDCS) seems to be an elegant way to optimize learning. Here we tested whether tDCS to the left dorsolateral prefrontal cortex or to the left posterior parietal cortex would boost recognition memory in general and/or particularly for action phrases enacted at study. During study, 48 young adults either read or enacted simple action phrases. Memory for the action phrases ... read more
    PubMed Abstract – tDCS and memory
  • Physiology of Transcranial Direct Current Stimulation.
    Related ArticlesPhysiology of Transcranial Direct Current Stimulation. J ECT. 2018 Jun 05;: Authors: Stagg CJ, Antal A, Nitsche MA Abstract Direct current stimulation is a neuromodulatory noninvasive brain stimulation tool, which was first introduced in animal and human experiments in the 1950s, and added to the standard arsenal of methods to alter brain physiology as well as psychological, motor, and behavioral processes and clinical symptoms in neurological and psychiatric diseases about 20 years ago. In contrast to other noninvasive brain stimulation tools, such as transcranial magnetic stimulation, it does not directly induce cerebral activity, but rather alters spontaneous brain activity ... read more
    PubMed Abstract – tDCS and memory
  • Transcranial direct current stimulation over the right DLPFC selectively modulates subprocesses in working memory.
    Related ArticlesTranscranial direct current stimulation over the right DLPFC selectively modulates subprocesses in working memory. PeerJ. 2018;6:e4906 Authors: Wang J, Tian J, Hao R, Tian L, Liu Q Abstract Background: Working memory, as a complex system, consists of two independent components: manipulation and maintenance process, which are defined as executive control and storage process. Previous studies mainly focused on the overall effect of transcranial direct current stimulation (tDCS) on working memory. However, little has been known about the segregative effects of tDCS on the sub-processes within working memory. Method: Transcranial direct current stimulation, as one of the non-invasive brain stimulation ... read more
    PubMed Abstract – tDCS and memory
  • Effects of Transcranial Direct Current Stimulation on Neural Networks in Young and Older Adults
    Related ArticlesEffects of Transcranial Direct Current Stimulation on Neural Networks in Young and Older Adults J Cogn Neurosci. 2017 11;29(11):1817-1828 Authors: Martin AK, Meinzer M, Lindenberg R, Sieg MM, Nachtigall L, Flöel A Abstract Transcranial direct current stimulation (tDCS) may be a viable tool to improve motor and cognitive function in advanced age. However, although a number of studies have demonstrated improved cognitive performance in older adults, other studies have failed to show restorative effects. The neural effects of beneficial stimulation response in both age groups is lacking. In the current study, tDCS was administered during simultaneous fMRI in 42 ... read more
    PubMed Abstract – tDCS and memory
  • Cognitive Training and Transcranial Direct Current Stimulation for Mild Cognitive Impairment in Parkinson’s Disease: A Randomized Controlled Trial.
    Related ArticlesCognitive Training and Transcranial Direct Current Stimulation for Mild Cognitive Impairment in Parkinson's Disease: A Randomized Controlled Trial. Parkinsons Dis. 2018;2018:4318475 Authors: Lawrence BJ, Gasson N, Johnson AR, Booth L, Loftus AM Abstract This study examined whether standard cognitive training, tailored cognitive training, transcranial direct current stimulation (tDCS), standard cognitive training + tDCS, or tailored cognitive training + tDCS improved cognitive function and functional outcomes in participants with PD and mild cognitive impairment (PD-MCI). Forty-two participants with PD-MCI were randomized to one of six groups: (1) standard cognitive training, (2) tailored cognitive training, (3) tDCS, (4) standard cognitive training + tDCS, (5) tailored cognitive training + tDCS, ... read more
    PubMed Abstract – tDCS and memory
  • Testing assumptions on prefrontal transcranial direct current stimulation: Comparison of electrode montages using multimodal fMRI.
    Related ArticlesTesting assumptions on prefrontal transcranial direct current stimulation: Comparison of electrode montages using multimodal fMRI. Brain Stimul. 2018 May 04;: Authors: Wörsching J, Padberg F, Goerigk S, Heinz I, Bauer C, Plewnia C, Hasan A, Ertl-Wagner B, Keeser D Abstract BACKGROUND: Transcranial direct current stimulation (tDCS) of the prefrontal cortex (PFC) has been widely applied in cognitive neurosciences and advocated as a therapeutic intervention, e.g. in major depressive disorder. Although several targets and protocols have been suggested, comparative studies of tDCS parameters, particularly electrode montages and their cortical targets, are still lacking. OBJECTIVE: This study investigated a priori hypotheses ... read more
    PubMed Abstract – tDCS and memory
  • tDCS Stimulation of the dlPFC Selectively Moderates the Detrimental Impact of Emotion on Analytical Reasoning.
    Related ArticlestDCS Stimulation of the dlPFC Selectively Moderates the Detrimental Impact of Emotion on Analytical Reasoning. Front Psychol. 2018;9:568 Authors: Trémolière B, Maheux-Caron V, Lepage JF, Blanchette I Abstract There is evidence of a detrimental effect of emotion on reasoning. Recent studies suggest that this relationship is mediated by working memory, a function closely associated with the dorsolateral prefrontal cortex (dlPFC). Relying on transcranial direct current stimulation (tDCS), the present research explores the possibility that anodal stimulation of the dlPFC has the potential to prevent the effect of emotion on analytical reasoning. Thirty-four participants took part in a lab experiment ... read more
    PubMed Abstract – tDCS and memory
  • Driving working memory with frequency-tuned noninvasive brain stimulation.
    Related ArticlesDriving working memory with frequency-tuned noninvasive brain stimulation. Ann N Y Acad Sci. 2018 Apr 29;: Authors: Albouy P, Baillet S, Zatorre RJ Abstract Frequency-tuned noninvasive brain stimulation is a recent approach in cognitive neuroscience that involves matching the frequency of transcranially applied electromagnetic fields to that of specific oscillatory components of the underlying neurophysiology. The objective of this method is to modulate ongoing/intrinsic brain oscillations, which correspond to rhythmic fluctuations of neural excitability, to causally change behavior. We review the impact of frequency-tuned noninvasive brain stimulation on the research field of human working memory. We argue that this ... read more
    PubMed Abstract – tDCS and memory
  • tDCS over left M1 or DLPFC does not improve learning of a bimanual coordination task.
    Related ArticlestDCS over left M1 or DLPFC does not improve learning of a bimanual coordination task. Sci Rep. 2016 10 25;6:35739 Authors: Vancleef K, Meesen R, Swinnen SP, Fujiyama H Abstract Previously, transcranial direct current stimulation (tDCS) over the primary motor cortex (M1) has resulted in improved performance in simple motor tasks. For a complex bimanual movement, studies using functional magnetic resonance imaging and transcranial magnetic stimulation indicated the involvement of the left dorsolateral prefrontal cortex (DLPFC) as well as left M1. Here we investigated the relative effect of up-regulating the cortical function in left DLPFC and left ... read more
    PubMed Abstract – tDCS and memory
  • Neurostimulation for Memory Enhancement in Epilepsy.
    Related ArticlesNeurostimulation for Memory Enhancement in Epilepsy. Curr Neurol Neurosci Rep. 2018 Apr 19;18(6):30 Authors: Meisenhelter S, Jobst BC Abstract PURPOSE OF REVIEW: Memory is one of the top concerns of epilepsy patients, but there are no known treatments to directly alleviate the memory deficits associated with epilepsy. Neurostimulation may provide new therapeutic tools to enhance memory in epilepsy patients. Here, we critically review recent investigations of memory enhancement using transcranial electrical stimulation (tES), transcranial magnetic stimulation (TMS), vagus nerve stimulation (VNS), chronic intracranial stimulation, and acute intracranial stimulation. RECENT FINDINGS: Existing literature suggests that transcranial direct current stimulation (tDCS) ... read more
    PubMed Abstract – tDCS and memory
  • Efficacy of transcranial direct current stimulation combined with cognitive training in the treatment of apathy in patients with Alzheimer’s disease: study protocol for a randomized trial.
    Related ArticlesEfficacy of transcranial direct current stimulation combined with cognitive training in the treatment of apathy in patients with Alzheimer's disease: study protocol for a randomized trial. Rev Recent Clin Trials. 2018 Apr 16;: Authors: Jean-Paul N, Boutoleau-Bretonniere C, Lefaucheur JP, Suarez A, Gaillard H, Chapelet G, Abad S, Van Langhenhove A, Nizard J, de Decke L Abstract BACKGROUND: Apathy, commonly defined as loss of motivation, is a symptom frequently encountered in Alzheimer's disease (AD). The treatment of apathy remains challenging in the absence of any truly effective medications. Transcranial magnetic stimulation (rTMS) or transcranial direct current stimulation (tDCS) can ... read more
    PubMed Abstract – tDCS and memory
  • Transcranial direct current stimulation improves long-term memory deficits in an animal model of attention-deficit/hyperactivity disorder and modulates oxidative and inflammatory parameters.
    Related ArticlesTranscranial direct current stimulation improves long-term memory deficits in an animal model of attention-deficit/hyperactivity disorder and modulates oxidative and inflammatory parameters. Brain Stimul. 2018 Apr 05;: Authors: Leffa DT, Bellaver B, Salvi AA, de Oliveira C, Caumo W, Grevet EH, Fregni F, Quincozes-Santos A, Rohde LA, Torres ILS Abstract BACKGROUND: Transcranial direct current stimulation (tDCS) is a technique that modulates neuronal activity and has been proposed as a potential therapeutic tool for attention-deficit/hyperactivity disorder (ADHD) symptoms. Although pilot studies have shown evidence of efficacy, its mechanism of action remains unclear. OBJECTIVE/HYPOTHESIS: We evaluated the effects of tDCS on behavioral ... read more
    PubMed Abstract – tDCS and memory
  • Cognitive Neuroscience of Attention Deficit Hyperactivity Disorder (ADHD) and Its Clinical Translation.
    Related ArticlesCognitive Neuroscience of Attention Deficit Hyperactivity Disorder (ADHD) and Its Clinical Translation. Front Hum Neurosci. 2018;12:100 Authors: Rubia K Abstract This review focuses on the cognitive neuroscience of Attention Deficit Hyperactivity Disorder (ADHD) based on functional magnetic resonance imaging (fMRI) studies and on recent clinically relevant applications such as fMRI-based diagnostic classification or neuromodulation therapies targeting fMRI deficits with neurofeedback (NF) or brain stimulation. Meta-analyses of fMRI studies of executive functions (EFs) show that ADHD patients have cognitive-domain dissociated complex multisystem impairments in several right and left hemispheric dorsal, ventral and medial fronto-cingulo-striato-thalamic and fronto-parieto-cerebellar networks that mediate cognitive ... read more
    PubMed Abstract – tDCS and memory
  • Can 8 months of daily tDCS application slow the cognitive decline in Alzheimer’s disease? A case study.
    Related ArticlesCan 8 months of daily tDCS application slow the cognitive decline in Alzheimer's disease? A case study. Neurocase. 2017 Apr;23(2):146-148 Authors: Bystad M, Rasmussen ID, Grønli O, Aslaksen PM Abstract This case study presents a patient with early-onset Alzheimer`s disease, who applied transcranial direct current stimulation (tDCS) daily for 8 consecutive months. This was a much higher frequency than previous tDCS studies. Neuropsychological assessments were conducted before the first tDCS session, after 5 months and after 8 months. After 8 months, the patient's immediate recall improved with 39%, whereas delayed recall improved 23%. Overall, the results revealed that patient's cognitive functions were ... read more
    PubMed Abstract – tDCS and memory
  • On the effectiveness of event-related beta tACS on episodic memory formation and motor cortex excitability.
    Related ArticlesOn the effectiveness of event-related beta tACS on episodic memory formation and motor cortex excitability. Brain Stimul. 2017 Sep - Oct;10(5):910-918 Authors: Braun V, Sokoliuk R, Hanslmayr S Abstract BACKGROUND: Transcranial alternating current stimulation (tACS) is widely used to entrain or modulate brain oscillations in order to investigate causal relationships between oscillations and cognition. OBJECTIVE: In a series of experiments we here addressed the question of whether event-related, transient tACS in the beta frequency range can be used to entrain beta oscillations in two different domains: episodic memory formation and motor cortex excitability. METHODS: In experiments 1 and ... read more
    PubMed Abstract – tDCS and memory
  • Cross-Species Neuromodulation from High-Intensity Transcranial Electrical Stimulation.
    Related ArticlesCross-Species Neuromodulation from High-Intensity Transcranial Electrical Stimulation. Trends Cogn Sci. 2018 Mar 27;: Authors: Widge AS Abstract Transcranial electrical stimulation (TES) is a proposed tool for noninvasively modulating human brain circuits, but its ability to affect cortical physiology remains unclear. A recent study merged TES with live animal and human cadaveric recordings to verify intracranial electrical effects, then used these findings to develop a novel neuromodulation protocol.PMID: 29602532 [PubMed - as supplied by publisher] ... read more
    PubMed Abstract – tDCS and memory
  • Self-generation and positivity effects following transcranial random noise stimulation in medial prefrontal cortex: A reality monitoring task in older adults.
    Related ArticlesSelf-generation and positivity effects following transcranial random noise stimulation in medial prefrontal cortex: A reality monitoring task in older adults. Cortex. 2017 06;91:186-196 Authors: Mammarella N, Di Domenico A, Palumbo R, Fairfield B Abstract Activation of medial Prefrontal Cortex (mPFC) has been typically found during reality monitoring tasks (i.e., distinguishing between internal self-generated vs external information). No study, however, has yet investigated whether transcranial Random Noise Stimulation (tRNS) over the mPFC leads to a reduction in reality-monitoring misattributions in aging. In particular, stimulating mPFC should increase the number of cognitive operations engaged while encoding and this distinctive information may ... read more
    PubMed Abstract – tDCS and memory
  • Effects of transcranial direct current stimulation on working memory and negative symptoms in schizophrenia: a phase II randomized sham-controlled trial.
    Related ArticlesEffects of transcranial direct current stimulation on working memory and negative symptoms in schizophrenia: a phase II randomized sham-controlled trial. Schizophr Res Cogn. 2018 Jun;12:20-28 Authors: Gomes JS, Trevizol AP, Ducos DV, Gadelha A, Ortiz BB, Fonseca AO, Akiba HT, Azevedo CC, Guimaraes LSP, Shiozawa P, Cordeiro Q, Lacerda A, Dias AM Abstract Background: The lack of efficacy of pharmacological treatments for cognitive and negative symptoms in schizophrenia highlights the need for new interventions. We investigated the effects of tDCS on working memory and negative symptoms in patients with schizophrenia. Method: Double-blinded, randomized, sham-controlled clinical trial, investigating the effects ... read more
    PubMed Abstract – tDCS and memory
  • Targeting the Cerebellum by Noninvasive Neurostimulation: a Review.
    Related ArticlesTargeting the Cerebellum by Noninvasive Neurostimulation: a Review. Cerebellum. 2017 Jun;16(3):695-741 Authors: van Dun K, Bodranghien F, Manto M, Mariën P Abstract Transcranial magnetic and electric stimulation of the brain are novel and highly promising techniques currently employed in both research and clinical practice. Improving or rehabilitating brain functions by modulating excitability with these noninvasive tools is an exciting new area in neuroscience. Since the cerebellum is closely connected with the cerebral regions subserving motor, associative, and affective functions, the cerebello-thalamo-cortical pathways are an interesting target for these new techniques. Targeting the cerebellum represents a novel way to ... read more
    PubMed Abstract – tDCS and memory