PubMed Abstract – tDCS and memory

  • Boosting working memory: uncovering the differential effects of tDCS and tACS
    Cereb Cortex Commun. 2022 May 7;3(2):tgac018. doi: 10.1093/texcom/tgac018. eCollection 2022.ABSTRACTWorking memory (WM) is essential for reasoning, decision-making, and problem solving. Recently, there has been an increasing effort in improving WM through noninvasive brain stimulation (NIBS), especially transcranial direct and alternating current stimulation (tDCS/tACS). Studies suggest that tDCS and tACS can modulate WM performance, but large variability in research approaches hinders the identification of optimal stimulation protocols and interpretation of study results. Moreover, it is unclear whether tDCS and tACS differentially affect WM. Here, we summarize and compare studies examining the effects of tDCS and tACS on WM performance in healthy ... read more
    PubMed Abstract – tDCS and memoryBy Daniel Senkowski
  • Transcranial Direct Current Stimulation (tDCS) as a Useful Rehabilitation Strategy to Improve Cognition in Patients With Alzheimer’s Disease and Parkinson’s Disease: An Updated Systematic Review of Randomized Controlled Trials
    Front Neurol. 2022 Feb 2;12:798191. doi: 10.3389/fneur.2021.798191. eCollection 2021.ABSTRACTAlzheimer's disease (AD) and Parkinson's disease (PD) are neurodegenerative disorders characterized by cognitive impairment and functional decline increasing with disease progression. Within non-pharmacological interventions, transcranial direct current stimulation (tDCS) might represent a cost-effective rehabilitation strategy to implement cognitive abilities with positive implications for functional autonomy and quality-of-life of patients. Our systematic review aimed at evaluating the effects of tDCS upon cognition in people suffering from AD and PD. We searched for randomized controlled trials (RCTs) into PubMed, Web of Science, and Cochrane Library. Three review authors extracted data of interest, with neuropsychological ... read more
    PubMed Abstract – tDCS and memoryBy Davide Maria Cammisuli
  • Neural oscillations promoting perceptual stability and perceptual memory during bistable perception
    Sci Rep. 2022 Feb 17;12(1):2760. doi: 10.1038/s41598-022-06570-4.ABSTRACTAmbiguous images elicit bistable perception, wherein periods of momentary perceptual stability are interrupted by sudden perceptual switches. When intermittently presented, ambiguous images trigger a perceptual memory trace in the intervening blank periods. Understanding the neural bases of perceptual stability and perceptual memory during bistable perception may hold clues for explaining the apparent stability of visual experience in the natural world, where ambiguous and fleeting images are prevalent. Motivated by recent work showing the involvement of the right inferior frontal gyrus (rIFG) in bistable perception, we conducted a transcranial direct-current stimulation (tDCS) study with a ... read more
    PubMed Abstract – tDCS and memoryBy Michael Zhu
  • NMDA receptor-related mechanisms of dopaminergic modulation of tDCS-induced neuroplasticity
    Cereb Cortex. 2022 Feb 15:bhac028. doi: 10.1093/cercor/bhac028. Online ahead of print.ABSTRACTDopamine is a key neuromodulator of neuroplasticity and an important neuronal substrate of learning, and memory formation, which critically involves glutamatergic N-methyl-D-aspartate (NMDA) receptors. Dopamine modulates NMDA receptor activity via dopamine D1 and D2 receptor subtypes. It is hypothesized that dopamine focuses on long-term potentiation (LTP)-like plasticity, i.e. reduces diffuse widespread but enhances locally restricted plasticity via a D2 receptor-dependent NMDA receptor activity reduction. Here, we explored NMDA receptor-dependent mechanisms underlying dopaminergic modulation of LTP-like plasticity induced by transcranial direct current stimulation (tDCS). Eleven healthy, right-handed volunteers received anodal tDCS ... read more
    PubMed Abstract – tDCS and memoryBy Elham Ghanavati
  • Brain activity and upper limb movement analysis in children with Down syndrome undergoing transcranial direct current stimulation combined with virtual reality training: study protocol for a randomized controlled trial
    Trials. 2022 Jan 28;23(1):87. doi: 10.1186/s13063-022-06014-4.ABSTRACTBACKGROUND: Children with Down syndrome have poorer functional and sensory skills compared to children with typical development. Virtual reality (VR) training could help improve these skills. Moreover, transcranial direct current stimulation (tDCS) has achieved promising results in terms of enhancing the effects of physical and sensory therapy by modulating cortical excitability.METHODS/DESIGN: Two investigations are proposed: (1) an observational study with a convenience sample consisting of children with Down syndrome (group 1-cognitive age of 6 to 12 years according to the Wechsler Abbreviated Scale of Intelligence) and children with typical development 6 to 12 years of ... read more
    PubMed Abstract – tDCS and memoryBy Jamile Benite Palma Lopes