PubMed Abstract – tDCS and memory

  • Transcranial Direct Current Stimulation Does Not Counteract Cognitive Fatigue, but Induces Sleepiness and an Inter-Hemispheric Shift in Brain Oxygenation.
    Related ArticlesTranscranial Direct Current Stimulation Does Not Counteract Cognitive Fatigue, but Induces Sleepiness and an Inter-Hemispheric Shift in Brain Oxygenation. Front Psychol. 2018;9:2351 Authors: Borragán G, Gilson M, Guerrero-Mosquera C, Di Ricci E, Slama H, Peigneux P Abstract Sustained cognitive demands may result in cognitive fatigue (CF), eventually leading to decreased behavioral performance and compromised brain resources. In the present study, we tested the hypothesis that transcranial direct current stimulation (tDCS) would counteract the behavioral and neurophysiological effects of CF. Twenty young healthy participants were tested in a within-subject counterbalanced order across two different days. Anodal tDCS (real vs. sham) ... read more
    PubMed Abstract – tDCS and memory
  • Transcranial direct current stimulation (tDCS) over parietal cortex improves associative memory.
    Related ArticlesTranscranial direct current stimulation (tDCS) over parietal cortex improves associative memory. Neurobiol Learn Mem. 2018 Dec 12;: Authors: Jovana B, Marija ČV, Marko Ž, Sladjan MD, Saša FR Abstract Associative memory plays a key role in everyday functioning, but it declines with normal aging as well as due to various pathological states and conditions, thus impairing quality of life. Associative memory enhancement via neurostimulation over frontal areas resulted in limited success, while posterior stimulation sites seemed to be more promising. We hypothesized that anodal transcranial direct current stimulation (tDCS) of parietal areas would lead to higher performance in associative ... read more
    PubMed Abstract – tDCS and memory
  • Prefronto-cerebellar neuromodulation affects appetite in obesity.
    Related ArticlesPrefronto-cerebellar neuromodulation affects appetite in obesity. Int J Obes (Lond). 2018 Dec 11;: Authors: Marron EM, Viejo-Sobera R, Cuatrecasas G, Redolar-Ripoll D, Lorda PG, Datta A, Bikson M, Magerowski G, Alonso-Alonso M Abstract Human neuroimaging studies have consistently reported changes in cerebellar function and integrity in association with obesity. To date, however, the nature of this link has not been studied directly. Emerging evidence suggests a role for the cerebellum in higher cognitive functions through reciprocal connections with the prefrontal cortex. The purpose of this exploratory study was to examine appetite changes associated with noninvasive prefronto-cerebellar neuromodulation in obesity. ... read more
    PubMed Abstract – tDCS and memory
  • Dose-Dependent Effects of Closed-Loop tACS Delivered During Slow-Wave Oscillations on Memory Consolidation.
    Related ArticlesDose-Dependent Effects of Closed-Loop tACS Delivered During Slow-Wave Oscillations on Memory Consolidation. Front Neurosci. 2018;12:867 Authors: Jones AP, Choe J, Bryant NB, Robinson CSH, Ketz NA, Skorheim SW, Combs A, Lamphere ML, Robert B, Gill HA, Heinrich MD, Howard MD, Clark VP, Pilly PK Abstract Sleep is critically important to consolidate information learned throughout the day. Slow-wave sleep (SWS) serves to consolidate declarative memories, a process previously modulated with open-loop non-invasive electrical stimulation, though not always effectively. These failures to replicate could be explained by the fact that stimulation has only been performed in open-loop, as opposed to closed-loop ... read more
    PubMed Abstract – tDCS and memory
  • A systematic review and meta-analysis of the effects of transcranial direct current stimulation (tDCS) on episodic memory.
    Related ArticlesA systematic review and meta-analysis of the effects of transcranial direct current stimulation (tDCS) on episodic memory. Brain Stimul. 2018 Nov 17;: Authors: Galli G, Vadillo MA, Sirota M, Feurra M, Medvedeva A Abstract BACKGROUND: In the past decade, several studies have examined the effects of transcranial direct current stimulation (tDCS) on long-term episodic memory formation and retrieval. These studies yielded conflicting results, likely due to differences in stimulation parameters, experimental design and outcome measures. OBJECTIVES: In this work we aimed to assess the robustness of tDCS effects on long-term episodic memory using a meta-analytical approach. METHODS: We conducted ... read more
    PubMed Abstract – tDCS and memory
  • Electrical stimulation over human posterior parietal cortex selectively enhances the capacity of visual short-term memory.
    Related ArticlesElectrical stimulation over human posterior parietal cortex selectively enhances the capacity of visual short-term memory. J Neurosci. 2018 Nov 20;: Authors: Wang S, Itthipuripat S, Ku Y Abstract Visual short-term memory (VSTM) provides an online mental space for incoming sensory information to be temporally maintained in order to carry out complex behavioral tasks. Despite its essential functions, the capacity at which VSTM could maintain sensory information is limited (i.e., VSTM can hold only about 3-4 visual items at once). Moreover, the quality of sensory representation (i.e., precision) degrades as more information has to be maintained in VSTM. Correlational evidence ... read more
    PubMed Abstract – tDCS and memory
  • Effect of transcranial direct current stimulation on cognitive function in stroke patients.
    Related ArticlesEffect of transcranial direct current stimulation on cognitive function in stroke patients. Egypt J Neurol Psychiatr Neurosurg. 2018;54(1):32 Authors: Shaker HA, Sawan SAE, Fahmy EM, Ismail RS, Elrahman SAEA Abstract Background: Cognitive impairment after stroke is common and can cause disability with major impacts on quality of life and independence. Transcranial direct current stimulation may represent a promising tool for reconstitution of cognitive functions in stroke patients. Objectives: This study aimed to investigate the effect of transcranial direct current stimulation on cognitive functions in stroke patients. Patients and methods: Forty male stroke patients were included. Patients were divided randomly ... read more
    PubMed Abstract – tDCS and memory
  • Transcranial direct current stimulation induces hippocampal metaplasticity mediated by brain-derived neurotrophic factor.
    Related ArticlesTranscranial direct current stimulation induces hippocampal metaplasticity mediated by brain-derived neurotrophic factor. Neuropharmacology. 2018 Nov 12;: Authors: Yu TH, Wu YJ, Chien ME, Hsu KS Abstract Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique used to modulate neuronal excitability via externally applied electric fields. Despite the positive effects of tDCS in a wide range of neurological disorders in humans, its mechanism of action remains poorly understood. Here we investigated cellular and molecular mechanisms underlying the aftereffects of anodal tDCS on the induction of long-term potentiation (LTP), a cellular correlate of learning and memory, at Schaffer collateral-CA1 ... read more
    PubMed Abstract – tDCS and memory
  • Randomized, crossover, sham-controlled, double-blind study of transcranial direct current stimulation of left DLPFC on executive functions .
    Related ArticlesRandomized, crossover, sham-controlled, double-blind study of transcranial direct current stimulation of left DLPFC on executive functions . Restor Neurol Neurosci. 2018 Nov 03;: Authors: Dumont L, El Mouderrib S, Théoret H Abstract BACKGROUND: Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique commonly used to modulate cognitive functions; so-called "anodal" stimulation is considered to increase cortical excitability while "cathodal" is presumed to have the opposite result. Yet, a growing number of recent studies question the robustness of this polarity-dependent effect, namely because of the important inter-individual variability with regards to tDCS modulatory effects. A plausible reason for ... read more
    PubMed Abstract – tDCS and memory
  • Verbal long-term memory is enhanced by retrieval practice but impaired by prefrontal direct current stimulation.
    Verbal long-term memory is enhanced by retrieval practice but impaired by prefrontal direct current stimulation. Brain Cogn. 2018 Nov 08;: Authors: Brunyé TT, Smith AM, Horner CB, Thomas AK Abstract Retrieval practice involves repeatedly testing a student during the learning experience, reliably conferring learning advantages relative to repeated study. Transcranial direct current stimulation (tDCS) of the left dorsolateral prefrontal cortex (dlPFC) has also been shown to confer learning advantages for verbal memory, though research is equivocal. The present study examined the effects of retrieval versus study practice with or without left dlPFC tDCS on verbal episodic memory. Participants (N = 150) experienced ... read more
    PubMed Abstract – tDCS and memory
  • Modulation of Working Memory Using Transcranial Electrical Stimulation: A Direct Comparison Between TACS and TDCS.
    Related ArticlesModulation of Working Memory Using Transcranial Electrical Stimulation: A Direct Comparison Between TACS and TDCS. Front Neurosci. 2018;12:761 Authors: Röhner F, Breitling C, Rufener KS, Heinze HJ, Hinrichs H, Krauel K, Sweeney-Reed CM Abstract Transcranial electrical stimulation (TES) has been considered a promising tool for improving working memory (WM) performance. Recent studies have demonstrated modulation of networks underpinning WM processing through application of transcranial alternating current (TACS) as well as direct current (TDCS) stimulation. Differences between study designs have limited direct comparison of the efficacy of these approaches, however. Here we directly compared the effects of theta TACS (6 ... read more
    PubMed Abstract – tDCS and memory
  • The COMT Val158 Met polymorphism does not modulate the after-effect of tDCS on working memory.
    Related ArticlesThe COMT Val158 Met polymorphism does not modulate the after-effect of tDCS on working memory. Eur J Neurosci. 2018 Nov 07;: Authors: Jongkees BJ, Loseva AA, Yavari FB, Nitsche MA, Colzato LS Abstract Transcranial direct current stimulation (tDCS) can alter cortical excitability, neural plasticity and cognitive-behavioral performance, however its effects are known to vary across studies. A partial account of this variability relates to individual differences in dopamine function. Indeed, dopaminergic manipulations alter the physiological and cognitive-behavioral effects of tDCS, and gene polymorphisms related to dopamine have predicted individual response to online tDCS (i.e., stimulation overlapping with the critical ... read more
    PubMed Abstract – tDCS and memory
  • Effects of transcranial direct current stimulation on episodic memory in amnestic mild cognitive impairment: A pilot study.
    Related ArticlesEffects of transcranial direct current stimulation on episodic memory in amnestic mild cognitive impairment: A pilot study. J Gerontol B Psychol Sci Soc Sci. 2018 Nov 05;: Authors: Manenti R, Sandrini M, Gobbi E, Binetti G, Cotelli M Abstract Objectives: Episodic memory is impaired in amnestic mild cognitive impairment (aMCI), which is posited as a potential prodromal form of Alzheimer's disease. Reactivated existing memories become sensitive to modification during reconsolidation. There is evidence that the lateral prefrontal cortex (PFC) plays causal role in episodic memory reconsolidation. Transcranial direct current stimulation (tDCS) applied to the PFC after a contextual reminder ... read more
    PubMed Abstract – tDCS and memory
  • Can Transcranial Direct-Current Stimulation Alone or Combined With Cognitive Training Be Used as a Clinical Intervention to Improve Cognitive Functioning in Persons With Mild Cognitive Impairment and Dementia? A Systematic Review and Meta-Analysis.
    Related ArticlesCan Transcranial Direct-Current Stimulation Alone or Combined With Cognitive Training Be Used as a Clinical Intervention to Improve Cognitive Functioning in Persons With Mild Cognitive Impairment and Dementia? A Systematic Review and Meta-Analysis. Front Hum Neurosci. 2018;12:416 Authors: Cruz Gonzalez P, Fong KNK, Chung RCK, Ting KH, Law LLF, Brown T Abstract Background: Transcranial direct-current stimulation (tDCS) facilitates cognitive improvement in healthy and pathological populations. It has been increasingly used in cases of mild cognitive impairment (MCI) and dementia. Our research question is: Can tDCS serve as a clinical intervention for improving the cognitive functions of persons with MCI ... read more
    PubMed Abstract – tDCS and memory
  • Effect of transcranial direct current stimulation on decision making and cognitive flexibility in gambling disorder.
    Related ArticlesEffect of transcranial direct current stimulation on decision making and cognitive flexibility in gambling disorder. Eur Arch Psychiatry Clin Neurosci. 2018 Oct 26;: Authors: Soyata AZ, Aksu S, Woods AJ, İşçen P, Saçar KT, Karamürsel S Abstract Decision making and cognitive flexibility are two components of cognitive control that play a critical role in the emergence, persistence, and relapse of gambling disorder. Transcranial direct current stimulation (tDCS) over the dorsolateral prefrontal cortex (DLPFC) has been reported to enhance decision making and cognitive flexibility in healthy volunteers and individuals with addictive disorders. In this triple-blind randomized sham-controlled parallel study, we ... read more
    PubMed Abstract – tDCS and memory
  • Effects of anodal tDCS on motor and cognitive function in a patient with multiple system atrophy.
    Related ArticlesEffects of anodal tDCS on motor and cognitive function in a patient with multiple system atrophy. Disabil Rehabil. 2018 Oct 21;:1-5 Authors: Alexoudi A, Patrikelis P, Fasilis T, Deftereos S, Sakas D, Gatzonis S Abstract PURPOSE: Multiple system atrophy (MSA) is a progressive neurodegenerative disease characterized by postural instability, autonomic failure, cerebellar ataxia, and cognitive deficits. There is currently no effective cure. Transcranial direct current stimulation (tDCS), offers promise in amendment of motor, and cognitive performance in advanced Parkinson's disease. CASE DESCRIPTION: We estimated the effect of anodal tDCS on motor and cognitive function in a 66-year-old woman with ... read more
    PubMed Abstract – tDCS and memory
  • Investigating the roles of medial prefrontal and superior temporal cortex in source monitoring.
    Related ArticlesInvestigating the roles of medial prefrontal and superior temporal cortex in source monitoring. Neuropsychologia. 2018 Oct 13;: Authors: Moseley P, Mitrenga KJ, Ellison A, Fernyhough C Abstract Source monitoring, or the ability to recall the origin of information, is a crucial aspect of remembering past experience. One facet of this, reality monitoring, refers to the ability to distinguish between internally generated and externally generated information, biases in which have previously been associated with auditory verbal hallucinations in schizophrenia. Neuroimaging evidence suggests that medial prefrontal and superior temporal (STG) regions may play a role in reality monitoring for auditory verbal ... read more
    PubMed Abstract – tDCS and memory
  • Inherent physiological artifacts in EEG during tDCS.
    Related ArticlesInherent physiological artifacts in EEG during tDCS. Neuroimage. 2018 Oct 12;: Authors: Gebodh N, Esmaeilpour Z, Adair D, Chelette K, Dmochowski J, Woods AJ, Kappenman ES, Parra LC, Bikson M Abstract Online imaging and neuromodulation is invalid if stimulation distorts measurements beyond the point of accurate measurement. In theory, combining transcranial Direct Current Stimulation (tDCS) with electroencephalography (EEG) is compelling, as both use non-invasive electrodes and image-guided dose can be informed by the reciprocity principle. To distinguish real changes in EEG from stimulation artifacts, prior studies applied conventional signal processing techniques (e.g. high-pass filtering, ICA). Here, we address the ... read more
    PubMed Abstract – tDCS and memory
  • Transcranial direct-current stimulation in ultra-treatment-resistant schizophrenia.
    Related ArticlesTranscranial direct-current stimulation in ultra-treatment-resistant schizophrenia. Brain Stimul. 2018 Oct 02;: Authors: Lindenmayer JP, Kulsa MKC, Sultana T, Kaur A, Yang R, Ljuri I, Parker B, Khan A Abstract BACKGROUND: Transcranial direct-current stimulation (tDCS), a non-invasive neurostimulation treatment, has been reported in a number of sham-controlled studies to show significant improvements in treatment-resistant auditory hallucinations in schizophrenia patients, primarily in ambulatory and higher-functioning patients, but little is known of the effects of tDCS on hospitalized, low-functioning inpatients. OBJECTIVE/HYPOTHESIS: The purpose of this study was to examine the efficacy and safety of tDCS for auditory hallucinations in hospitalized ultra-treatment-resistant schizophrenia ... read more
    PubMed Abstract – tDCS and memory
  • Bayesian analysis of the effect of transcranial direct current stimulation on experimental pain sensitivity in older adults with knee osteoarthritis: randomized sham-controlled pilot clinical study.
    Related ArticlesBayesian analysis of the effect of transcranial direct current stimulation on experimental pain sensitivity in older adults with knee osteoarthritis: randomized sham-controlled pilot clinical study. J Pain Res. 2018;11:2071-2082 Authors: Ahn H, Suchting R, Woods AJ, Miao H, Green C, Cho RY, Choi E, Fillingim RB Abstract Purpose: Previous studies have indicated that transcranial direct current stimulation (tDCS) with the anode over the motor cortex and the cathode over the contralateral supraorbital region is effective in reducing clinical pain in patients with chronic pain, but these studies have not focused on experimental pain sensitivity. Therefore, the aim of this ... read more
    PubMed Abstract – tDCS and memory
  • Cerebellar transcranial direct current stimulation improves adaptive postural control.
    Related ArticlesCerebellar transcranial direct current stimulation improves adaptive postural control. Clin Neurophysiol. 2018 01;129(1):33-41 Authors: Poortvliet P, Hsieh B, Cresswell A, Au J, Meinzer M Abstract OBJECTIVE: Rehabilitation interventions contribute to recovery of impaired postural control, but it remains a priority to optimize their effectiveness. A promising strategy may involve transcranial direct current stimulation (tDCS) of brain areas involved in fine-tuning of motor adaptation. This study explored the effects of cerebellar tDCS (ctDCS) on postural recovery from disturbance by Achilles tendon vibration. METHODS: Twenty-eight healthy volunteers participated in this sham-ctDCS controlled study. Standing blindfolded on a force platform, four ... read more
    PubMed Abstract – tDCS and memory
  • Remotely Supervised Transcranial Direct Current Stimulation Increases the Benefit of At-Home Cognitive Training in Multiple Sclerosis.
    Related ArticlesRemotely Supervised Transcranial Direct Current Stimulation Increases the Benefit of At-Home Cognitive Training in Multiple Sclerosis. Neuromodulation. 2018 Jun;21(4):383-389 Authors: Charvet L, Shaw M, Dobbs B, Frontario A, Sherman K, Bikson M, Datta A, Krupp L, Zeinapour E, Kasschau M Abstract OBJECTIVE: To explore the efficacy of remotely-supervised transcranial direct current stimulation (RS-tDCS) paired with cognitive training (CT) exercise in participants with multiple sclerosis (MS). METHODS: In a feasibility study of RS-tDCS in MS, participants completed ten sessions of tDCS paired with CT (1.5 mA × 20 min, dorsolateral prefrontal cortex montage). RS-tDCS participants were compared to ... read more
    PubMed Abstract – tDCS and memory
  • Beneficial effects of anodal transcranial direct current stimulation (tDCS) on spatial working memory in patients with schizophrenia.
    Related ArticlesBeneficial effects of anodal transcranial direct current stimulation (tDCS) on spatial working memory in patients with schizophrenia. Eur Neuropsychopharmacol. 2018 Oct 03;: Authors: Schwippel T, Papazova I, Strube W, Fallgatter AJ, Hasan A, Plewnia C Abstract Schizophrenia is a severe and often detrimental psychiatric disorder. The individual patients' level of functioning is essentially determined by cognitive, particularly working memory (WM), deficits that are critically linked to dysfunctional activity of the dorsolateral prefrontal cortex (dlPFC). Transcranial direct current stimulation (tDCS) can transiently modulate activity of the dlPFC and remote areas and has been shown to improve WM functions. It may ... read more
    PubMed Abstract – tDCS and memory
  • Transcranial direct-current stimulation (tDCS) improves detection of simple bright stimuli by amblyopic Long Evans rats in the SLAG task and produces an increase of parvoalbumin labelled cells in visual cortices.
    Related ArticlesTranscranial direct-current stimulation (tDCS) improves detection of simple bright stimuli by amblyopic Long Evans rats in the SLAG task and produces an increase of parvoalbumin labelled cells in visual cortices. Brain Res. 2018 Oct 01;: Authors: Castaño-Castaño S, Martinez-Navarrete G, Morales-Navas M, Fernadez-Jover E, Sanchez-Santed F, Nieto-Escámez F Abstract In this work visual functional improvement of amblyopic Long Evans rats treated with tDCS has been assessed using the "slow angled-descent forepaw grasping" (SLAG) test. This test is based on an innate response that does not requires any memory-learning component and has been used before for measuring visual function in ... read more
    PubMed Abstract – tDCS and memory
  • Effects of Non-invasive Neuromodulation on Executive and Other Cognitive Functions in Addictive Disorders: A Systematic Review.
    Related ArticlesEffects of Non-invasive Neuromodulation on Executive and Other Cognitive Functions in Addictive Disorders: A Systematic Review. Front Neurosci. 2018;12:642 Authors: Schluter RS, Daams JG, van Holst RJ, Goudriaan AE Abstract Background: In order to improve the current treatment of addictive disorders non-invasive neuromodulation over the dorsolateral prefrontal cortex (DLPFC) has gained attention. The DLPFC is crucially involved in executive functioning, functions which are related to the course of addictive disorders. Non-invasive stimulation of the DLPFC may lead to changes in executive functioning. Currently an overview of effects of neuromodulation on these functions is lacking. Therefore, this systematic review addresses ... read more
    PubMed Abstract – tDCS and memory
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