PubMed Abstract – tDCS and memory

  • Transcranial direct current stimulation in attention-deficit hyperactivity disorder: A meta-analysis of neuropsychological deficits.
    Related ArticlesTranscranial direct current stimulation in attention-deficit hyperactivity disorder: A meta-analysis of neuropsychological deficits. PLoS One. 2019;14(4):e0215095 Authors: Salehinejad MA, Wischnewski M, Nejati V, Vicario CM, Nitsche MA Abstract Transcranial direct current stimulation (tDCS) is a promising method for altering cortical excitability with clinical implications in neuropsychiatric diseases. Its application in neurodevelopmental disorders especially attention-deficit hyperactivity disorder (ADHD), is in early stage and promising but its effectiveness has not been systematically examined yet. We conducted a meta-analysis on the effectiveness of tDCS on the most studied neuropsychological symptoms of ADHD, which is the first reported meta-analysis of tDCS studies on ... read more
    6 days ago
  • Adjunct transcranial direct current stimulation improves cognitive function in patients with schizophrenia: A double-blind 12-week study.
    Related ArticlesAdjunct transcranial direct current stimulation improves cognitive function in patients with schizophrenia: A double-blind 12-week study. Schizophr Res. 2018 Jul;197:378-385 Authors: Jeon DW, Jung DU, Kim SJ, Shim JC, Moon JJ, Seo YS, Jung SS, Seo BJ, Kim JE, Oh M, Kim YN Abstract OBJECTIVES: Cognitive impairment is a common symptom of schizophrenia that has significant effects on quality of life and the activities of daily living. The present study examined the ability of transcranial direct current stimulation (tDCS) to improve cognitive function and clinical symptoms in patients with schizophrenia. METHODS: Fifty-six patients with schizophrenia were randomized to ... read more
    1 week ago
  • Systematic Review Investigating the Effects of Nonpharmacological Interventions During Sleep to Enhance Physical Rehabilitation Outcomes in People With Neurological Diagnoses.
    Related ArticlesSystematic Review Investigating the Effects of Nonpharmacological Interventions During Sleep to Enhance Physical Rehabilitation Outcomes in People With Neurological Diagnoses. Neurorehabil Neural Repair. 2019 Apr 02;:1545968319840288 Authors: Johnson BP, Shipper AG, Westlake KP Abstract OBJECTIVE: Conduct a systematic review of nonpharmacological interventions applied during sleep to enhance physical rehabilitation outcomes of individuals with a neurological diagnosis. DATA SOURCES: Three online databases were searched for original research. STUDY SELECTION: Intervention studies were included that used outcome measures of impairment, activity, and/or participation. DATA EXTRACTION: Two reviewers independently screened 2287 titles and abstracts, reviewed 101 full texts, extracted data, and ... read more
    2 weeks ago
  • Transcranial direct current stimulation over the right and left VLPFC leads to differential effects on working and episodic memory.
    Related ArticlesTranscranial direct current stimulation over the right and left VLPFC leads to differential effects on working and episodic memory. Brain Cogn. 2019 Mar 30;132:98-107 Authors: Weintraub-Brevda RR, Chua EF Abstract Previous research suggests that the left VLPFC is involved in working memory, whereas right VLPFC is involved with subsequent episodic memory. High-Definition Transcranial Direct Current Stimulation (HD-tDCS) was used to test whether excitation of the left or right VLPFC would show differential effects of negative and neutral stimuli on working memory and episodic memory tasks. While receiving HD-tDCS over the left or right VLPFC or sham stimulation, participants ... read more
    2 weeks ago
  • Effects of in-Scanner Bilateral Frontal tDCS on Functional Connectivity of the Working Memory Network in Older Adults.
    Related ArticlesEffects of in-Scanner Bilateral Frontal tDCS on Functional Connectivity of the Working Memory Network in Older Adults. Front Aging Neurosci. 2019;11:51 Authors: Nissim NR, O'Shea A, Indahlastari A, Telles R, Richards L, Porges E, Cohen R, Woods AJ Abstract Working memory is an executive memory process essential for everyday decision-making and problem solving that declines with advanced age. Transcranial direct current stimulation (tDCS) is a non-invasive form of brain stimulation that has demonstrated potential for improving working memory performance in older adults. However, the neural mechanisms underlying effects of tDCS on working memory are not well understood. This ... read more
    2 weeks ago
  • Can Slow-Wave Sleep Enhancement Improve Memory? A Review of Current Approaches and Cognitive Outcomes.
    Related ArticlesCan Slow-Wave Sleep Enhancement Improve Memory? A Review of Current Approaches and Cognitive Outcomes. Yale J Biol Med. 2019 Mar;92(1):63-80 Authors: Zhang Y, Gruber R Abstract Slow-wave sleep (SWS) is involved in the overnight consolidation of declarative memories. Recent efforts using auditory stimulation, slow-oscillatory transcranial direct current stimulation (so-tDCS), and pharmacological agents have targeted sleep slow-waves as a method for enhancing cognitive performance. However, no studies thus far have integrated current evidence to provide a preliminary review of the effects of SWS enhancement on memory and other cognitive outcomes. The objective of this review was to synthesize the results ... read more
    3 weeks ago
  • tACS motor system effects can be caused by transcutaneous stimulation of peripheral nerves.
    Related ArticlestACS motor system effects can be caused by transcutaneous stimulation of peripheral nerves. Nat Commun. 2019 01 17;10(1):266 Authors: Asamoah B, Khatoun A, Mc Laughlin M Abstract Transcranial alternating current stimulation (tACS) is a noninvasive neuromodulation method which has been shown to modulate hearing, motor, cognitive and memory function. However, the mechanisms underpinning these findings are controversial, as studies show that the current reaching the cortex may not be strong enough to entrain neural activity. Here, we propose a new hypothesis to reconcile these opposing results: tACS effects are caused by transcutaneous stimulation of peripheral nerves in ... read more
    4 weeks ago
  • Non-invasive Cognitive Enhancement in Epilepsy.
    Related ArticlesNon-invasive Cognitive Enhancement in Epilepsy. Front Neurol. 2019;10:167 Authors: Jacobs CS, Willment KC, Sarkis RA Abstract Epilepsy patients frequently experience cognitive difficulties, particularly in the domains of memory, attention, and executive function. Despite the frequency of these difficulties among epilepsy patients, current strategies to treat cognitive dysfunction are limited. We performed a systematic review of controlled trials of non-invasive cognitive enhancement in epilepsy. We identified studies examining the efficacy of pharmacological agents, namely the acetylcholinesterase inhibitors donepezil and galantamine, the NMDA non-competitive antagonist memantine, and the stimulant methylphenidate, as well as non-invasive non-pharmacological transcranial magnetic stimulation (TMS) and ... read more
    4 weeks ago
  • The immediate and delayed effects of single tDCS session over posterior parietal cortex on face-word associative memory.
    Related ArticlesThe immediate and delayed effects of single tDCS session over posterior parietal cortex on face-word associative memory. Behav Brain Res. 2019 Mar 14;: Authors: Bjekić J, Vulić K, Živanović M, Vujičić J, Ljubisavljević M, Filipović SR Abstract Associative memory (AM), an ability to form and retrieve associations between information units is crucial for everyday functioning and is affected by ageing as well as by different neurological conditions. It was shown that rTMS over posterior parietal cortex (PPC) can improve AM of face-word pairs. Therefore, we examined if tDCS will produce comparable effects and explore whether the effect would ... read more
    1 month ago
  • New information on the effects of transcranial direct current stimulation on n-back task performance.
    Related ArticlesNew information on the effects of transcranial direct current stimulation on n-back task performance. Exp Brain Res. 2019 Mar 14;: Authors: Mashal N, Metzuyanim-Gorelick S Abstract The n-back task is prototypical tool widely used to evaluate working memory (WM) abilities in healthy and clinical populations. Previous studies finding beneficial effects of transcranial direct current stimulation (tDCS) over the dorsal lateral prefrontal cortex (DLPFC) on n-back task performance were limited by the number of n-back "memory loads" utilized and the assessment of performance only immediately following stimulation. Our aims were to investigate both the immediate and lasting effects of six ... read more
    1 month ago
  • Methods to Compare Predicted and Observed Phosphene Experience in tACS Subjects.
    Related ArticlesMethods to Compare Predicted and Observed Phosphene Experience in tACS Subjects. Neural Plast. 2018;2018:8525706 Authors: Indahlastari A, Kasinadhuni AK, Saar C, Castellano K, Mousa B, Chauhan M, Mareci TH, Sadleir RJ Abstract Background: Phosphene generation is an objective physical measure of potential transcranial alternating current stimulation (tACS) biological side effects. Interpretations from phosphene analysis can serve as a first step in understanding underlying mechanisms of tACS in healthy human subjects and assist validation of computational models. Objective/Hypothesis: This preliminary study introduces and tests methods to analyze predicted phosphene occurrence using computational head models constructed from tACS recipients ... read more
    1 month ago
  • Repetitive Transcranial Magnetic Stimulation changes absolute theta power during cognitive/motor tasks.
    Related ArticlesRepetitive Transcranial Magnetic Stimulation changes absolute theta power during cognitive/motor tasks. Neurosci Lett. 2018 11 20;687:77-81 Authors: Di Giacomo J, Gongora M, Silva F, Vicente R, Arias-Carrion O, Orsini M, Teixeira S, Cagy M, Velasques B, Ribeiro P Abstract Repetitive Transcranial Magnetic Stimulation (rTMS) studies are used to test motor imagery hypothesis. Motor Imagery (MI) represents conscious access to contents of movement intention, generally executed unconsciously during motor preparation. The main objective of this study was to investigate electrophysiological changes, which occurred before and after low-frequency rTMS application when we compared three different tasks: execution, action observation and ... read more
    1 month ago
  • Slow oscillatory transcranial direct current stimulation (so-tDCS) during slow wave sleep has no effects on declarative memory in healthy young subjects.
    Related ArticlesSlow oscillatory transcranial direct current stimulation (so-tDCS) during slow wave sleep has no effects on declarative memory in healthy young subjects. Brain Stimul. 2019 Feb 21;: Authors: Bueno-Lopez A, Eggert T, Dorn H, Danker-Hopfe H Abstract BACKGROUND: The manipulation of specific brain oscillations by applying transcranial electrical stimulation techniques in order to enhance memory processes during sleep has become an intriguing field of research. A seminal study found a positive effect of slow-oscillatory transcranial direct current stimulation (so-tDCS) on sleep-dependent consolidation of declarative memories. Since then several studies have tried to replicate this result with inconsistent findings. OBJECTIVE/HYPOTHESIS: ... read more
    1 month ago
  • Cross-Species Neuromodulation from High-Intensity Transcranial Electrical Stimulation.
    Related ArticlesCross-Species Neuromodulation from High-Intensity Transcranial Electrical Stimulation. Trends Cogn Sci. 2018 05;22(5):372-374 Authors: Widge AS Abstract Transcranial electrical stimulation (TES) is a proposed tool for noninvasively modulating human brain circuits, but its ability to affect cortical physiology remains unclear. A recent study merged TES with live animal and human cadaveric recordings to verify intracranial electrical effects, then used these findings to develop a novel neuromodulation protocol.PMID: 29602532 [PubMed - indexed for MEDLINE] ... read more
    1 month ago
  • Inherent physiological artifacts in EEG during tDCS.
    Related ArticlesInherent physiological artifacts in EEG during tDCS. Neuroimage. 2019 01 15;185:408-424 Authors: Gebodh N, Esmaeilpour Z, Adair D, Chelette K, Dmochowski J, Woods AJ, Kappenman ES, Parra LC, Bikson M Abstract Online imaging and neuromodulation is invalid if stimulation distorts measurements beyond the point of accurate measurement. In theory, combining transcranial Direct Current Stimulation (tDCS) with electroencephalography (EEG) is compelling, as both use non-invasive electrodes and image-guided dose can be informed by the reciprocity principle. To distinguish real changes in EEG from stimulation artifacts, prior studies applied conventional signal processing techniques (e.g. high-pass filtering, ICA). Here, we address ... read more
    1 month ago
  • Cognitive effects of non-surgical brain stimulation for major depressive disorder: protocol for a systematic review and meta-analysis.
    Related ArticlesCognitive effects of non-surgical brain stimulation for major depressive disorder: protocol for a systematic review and meta-analysis. BMJ Open. 2019 Feb 19;9(2):e023796 Authors: Kiebs M, Hurlemann R, Mutz J Abstract INTRODUCTION: Non-surgical brain stimulation techniques may be considered as alternative or add-on treatments for patients with major depressive disorder who failed to respond to pharmacological interventions. Electroconvulsive therapy has been shown to be highly effective in reducing depressive symptoms but stakeholders remain concerned about adverse cognitive effects. Repetitive transcranial magnetic stimulation and transcranial direct current stimulation may be associated with more benign adverse effect profiles and may indeed improve ... read more
    2 months ago
  • tDCS-induced episodic memory enhancement and its association with functional network coupling in older adults.
    Related ArticlestDCS-induced episodic memory enhancement and its association with functional network coupling in older adults. Sci Rep. 2019 Feb 19;9(1):2273 Authors: Antonenko D, Hayek D, Netzband J, Grittner U, Flöel A Abstract Transcranial direct current stimulation (tDCS) augments training-induced cognitive gains, an issue of particular relevance in the aging population. However, negative outcomes have been reported as well, and few studies so far have evaluated the impact of tDCS on episodic memory formation in elderly cohorts. The heterogeneity of previous findings highlights the importance of elucidating neuronal underpinnings of tDCS-induced modulations, and of determining individual predictors of a positive response. ... read more
    2 months ago
  • The Effects of Transcranial Direct Current Stimulation (tDCS) on Working Memory Training in Healthy Young Adults.
    Related ArticlesThe Effects of Transcranial Direct Current Stimulation (tDCS) on Working Memory Training in Healthy Young Adults. Front Hum Neurosci. 2019;13:19 Authors: Ke Y, Wang N, Du J, Kong L, Liu S, Xu M, An X, Ming D Abstract Working memory (WM) is a fundamental cognitive ability to support complex thought, but it is limited in capacity. WM training has shown the potential benefit for those in need of a higher WM ability. Many studies have shown the potential of transcranial direct current stimulation (tDCS) to transiently enhance WM performance by delivering a low current to the brain cortex of ... read more
    2 months ago
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