Pubmed – tDCS and Cognition

  • Editorial: Modulating Cortical Dynamics in Language, Speech and Music.
    Related ArticlesEditorial: Modulating Cortical Dynamics in Language, Speech and Music. Front Integr Neurosci. 2018;12:58 Authors: Hartwigsen G, Scharinger M, Sammler D PMID: 30538623 [PubMed] ... read more
    Pubmed – tDCS and Cognition
  • Medial prefrontal cortex stimulation modulates irony processing as indexed by the N400.
    Related ArticlesMedial prefrontal cortex stimulation modulates irony processing as indexed by the N400. Soc Neurosci. 2018 08;13(4):495-510 Authors: Baptista NI, Manfredi M, Boggio PS Abstract In this study, we investigated whether the ERP responses observed during a verbal irony comprehension task might represent the cortical manifestation of the Medial Prefrontal Cortex (MPFC) activity. We performed a tDCS-EEG study in which we analyzed the effects of tDCS polarities (anode, cathode, sham) over the MPFC during a verbal irony task. We presented visual short stories portraying everyday situations followed by written statements in either an ironic or literal condition, whose meaning was ... read more
    Pubmed – tDCS and Cognition
  • Transcranial alternating current stimulation with speech envelopes modulates speech comprehension.
    Related ArticlesTranscranial alternating current stimulation with speech envelopes modulates speech comprehension. Neuroimage. 2018 05 15;172:766-774 Authors: Wilsch A, Neuling T, Obleser J, Herrmann CS Abstract Cortical entrainment of the auditory cortex to the broadband temporal envelope of a speech signal is crucial for speech comprehension. Entrainment results in phases of high and low neural excitability, which structure and decode the incoming speech signal. Entrainment to speech is strongest in the theta frequency range (4-8 Hz), the average frequency of the speech envelope. If a speech signal is degraded, entrainment to the speech envelope is weaker and speech intelligibility declines. Besides ... read more
    Pubmed – tDCS and Cognition
  • Transcranial Alternating Current Stimulation Modulates Risky Decision Making in a Frequency-Controlled Experiment.
    Related ArticlesTranscranial Alternating Current Stimulation Modulates Risky Decision Making in a Frequency-Controlled Experiment. eNeuro. 2017 Nov-Dec;4(6): Authors: Yaple Z, Martinez-Saito M, Awasthi B, Feurra M, Shestakova A, Klucharev V Abstract In this study, we investigated the effect of transcranial alternating current stimulation (tACS) on voluntary risky decision making and executive control in humans. Stimulation was delivered online at 5 Hz (θ), 10 Hz (α), 20 Hz (β), and 40 Hz (γ) on the left and right frontal area while participants performed a modified risky decision-making task. This task allowed participants to voluntarily select between risky and certain decisions associated ... read more
    Pubmed – tDCS and Cognition
  • Remotely-supervised transcranial direct current stimulation paired with cognitive training in Parkinson’s disease: An open-label study.
    Related ArticlesRemotely-supervised transcranial direct current stimulation paired with cognitive training in Parkinson's disease: An open-label study. J Clin Neurosci. 2018 Nov;57:51-57 Authors: Agarwal S, Pawlak N, Cucca A, Sharma K, Dobbs B, Shaw M, Charvet L, Biagioni M Abstract BACKGROUND: Transcranial direct current stimulation (tDCS) has been explored as a potential intervention in Parkinson's disease (PD) and recent studies have shown promising results in cognitive, gait and motor function. However, evidence of efficacy is limited due to small size studies, short treatment periods, lack of standardization of methodologies and other study design limitations. Remotely supervised-tDCS (RS-tDCS) allows "at-home" study ... read more
    Pubmed – tDCS and Cognition
  • A systematic review and meta-analysis of the effects of transcranial direct current stimulation (tDCS) on episodic memory.
    Related ArticlesA systematic review and meta-analysis of the effects of transcranial direct current stimulation (tDCS) on episodic memory. Brain Stimul. 2018 Nov 17;: Authors: Galli G, Vadillo MA, Sirota M, Feurra M, Medvedeva A Abstract BACKGROUND: In the past decade, several studies have examined the effects of transcranial direct current stimulation (tDCS) on long-term episodic memory formation and retrieval. These studies yielded conflicting results, likely due to differences in stimulation parameters, experimental design and outcome measures. OBJECTIVES: In this work we aimed to assess the robustness of tDCS effects on long-term episodic memory using a meta-analytical approach. METHODS: We conducted ... read more
    Pubmed – tDCS and Cognition
  • The Effect of High-Definition Transcranial Direct Current Stimulation of the Right Inferior Frontal Gyrus on Empathy in Healthy Individuals.
    Related ArticlesThe Effect of High-Definition Transcranial Direct Current Stimulation of the Right Inferior Frontal Gyrus on Empathy in Healthy Individuals. Front Hum Neurosci. 2018;12:446 Authors: Wu X, Xu F, Chen X, Wang L, Huang W, Wan K, Ji GJ, Xiao G, Xu S, Yu F, Zhu C, Xi C, Wang K Abstract Empathy, including cognitive and emotional empathy, refers to the ability to infer the mental states of others and to the capacity to share emotions. The neural mechanisms involved in empathy are complex and not yet fully understood, and previous studies have shown that both cognitive and emotional empathy ... read more
    Pubmed – tDCS and Cognition
  • No Effect of the Right Posterior Parietal Cortex tDCS in Dual-Target Visual Search.
    Related ArticlesNo Effect of the Right Posterior Parietal Cortex tDCS in Dual-Target Visual Search. Front Psychol. 2018;9:2112 Authors: Lanina AA, Feurra M, Gorbunova ES Abstract "Subsequent search misses" represent a decrease in accuracy at detecting a second target in a visual search task. In this study, we tested the possibility to modulate this effect via inhibition of the right posterior parietal cortex trough transcranial direct current stimulation (tDCS). The target stimuli were T-shapes presented among L-shaped distractors. The participant's task was to detect targets or to report their absence. For each trial, targets could be represented by one high-salient target, ... read more
    Pubmed – tDCS and Cognition
  • Lack of effect of transcranial direct current stimulation (tDCS) on short-term smoking cessation: Results of a randomized, sham-controlled clinical trial.
    Related ArticlesLack of effect of transcranial direct current stimulation (tDCS) on short-term smoking cessation: Results of a randomized, sham-controlled clinical trial. Drug Alcohol Depend. 2018 Nov 13;194:244-251 Authors: Falcone M, Bernardo L, Wileyto EP, Allenby C, Burke AM, Hamilton R, Cristancho M, Ashare RL, Loughead J, Lerman C Abstract BACKGROUND: Transcranial direct current stimulation (tDCS) has been shown to improve measures of executive cognitive function and reduce cigarette consumption. Studies conducted to date have been small, and the results are mixed. METHODS: This randomized, double-blind, parallel arm clinical trial tested the effects of active anodal tDCS targeted to the left ... read more
    Pubmed – tDCS and Cognition
  • Optimal Combination of Anodal Transcranial Direct Current Stimulations and Motor Imagery Interventions.
    Related ArticlesOptimal Combination of Anodal Transcranial Direct Current Stimulations and Motor Imagery Interventions. Neural Plast. 2018;2018:5351627 Authors: Saruco E, Di Rienzo F, Nunez-Nagy S, Rubio-Gonzalez MA, Debarnot U, Collet C, Guillot A, Saimpont A Abstract Motor imagery contributes to enhance the (re)learning of motor skills through remapping of cortical networks. Combining motor imagery with anodal transcranial direct-current stimulation (a-tDCS) over the primary motor cortex has further been shown to promote its beneficial effects on postural control. Whether motor imagery should be performed concomitantly to a-tDCS (over depolarized membrane) or consecutively (over changing neurotransmitters activity) remains to be elucidated. ... read more
    Pubmed – tDCS and Cognition
  • Cognitive Rehabilitation and Transcranial Direct Current Stimulation in a Patient with Posterior Cortical Atrophy: An fMRI Study.
    Related ArticlesCognitive Rehabilitation and Transcranial Direct Current Stimulation in a Patient with Posterior Cortical Atrophy: An fMRI Study. Am J Case Rep. 2018 Jun 21;19:729-733 Authors: Gramegna LL, Evangelisti S, Testa C, Baiardi S, Mitolo M, Capellari S, Stracciari A, Poda R, Di Stasi V, Cretella L, Lodi R, Tonon C, Liguori R Abstract BACKGROUND Posterior cortical atrophy (PCA) is a neurodegenerative syndrome that accounts for 5% of the atypical presentation of Alzheimer disease (AD). To date, only a few studies have explored the effect of non-pharmacological treatment in PCA patients and no studies have evaluated the efficacy of ... read more
    Pubmed – tDCS and Cognition
  • The place of transcranial direct current stimulation in the management of multiple sclerosis-related symptoms.
    Related ArticlesThe place of transcranial direct current stimulation in the management of multiple sclerosis-related symptoms. Neurodegener Dis Manag. 2018 Nov 19;: Authors: Ayache SS, Chalah MA Abstract Multiple sclerosis (MS) is an autoimmune disease of the central nervous system, characterized by chronic inflammation, demyelination, synaptopathy and neurodegeneration. Patients may exhibit sensory, motor, cognitive, emotional and behavioral symptoms throughout their disease process. Nowadays, the challenge is to find optimal treatment for MS symptoms, especially that available pharmacological interventions are faced by modest therapeutic outcomes and numerous side effects. Thus, finding alternative strategies might be of help in this context. The aim ... read more
    Pubmed – tDCS and Cognition
  • The COMT Val158 Met polymorphism does not modulate the after-effect of tDCS on working memory.
    Related ArticlesThe COMT Val158 Met polymorphism does not modulate the after-effect of tDCS on working memory. Eur J Neurosci. 2018 Nov 07;: Authors: Jongkees BJ, Loseva AA, Yavari FB, Nitsche MA, Colzato LS Abstract Transcranial direct current stimulation (tDCS) can alter cortical excitability, neural plasticity and cognitive-behavioral performance, however its effects are known to vary across studies. A partial account of this variability relates to individual differences in dopamine function. Indeed, dopaminergic manipulations alter the physiological and cognitive-behavioral effects of tDCS, and gene polymorphisms related to dopamine have predicted individual response to online tDCS (i.e., stimulation overlapping with the ... read more
    Pubmed – tDCS and Cognition
  • Anodal Transcranial Direct-Current Stimulation Over the Right Dorsolateral Prefrontal Cortex Influences Emotional Face Perception.
    Related ArticlesAnodal Transcranial Direct-Current Stimulation Over the Right Dorsolateral Prefrontal Cortex Influences Emotional Face Perception. Neurosci Bull. 2018 Oct;34(5):842-848 Authors: Yang LC, Ren P, Ma YY Abstract The dorsolateral prefrontal cortex (DLPFC) is considered to play a crucial role in many high-level functions, such as cognitive control and emotional regulation. Many studies have reported that the DLPFC can be activated during the processing of emotional information in tasks requiring working memory. However, it is still not clear whether modulating the activity of the DLPFC influences emotional perception in a detection task. In the present study, using transcranial direct-current ... read more
    Pubmed – tDCS and Cognition
  • Too Fast or Too Slow? Time and Neuronal Variability in Bipolar Disorder-A Combined Theoretical and Empirical Investigation.
    Related ArticlesToo Fast or Too Slow? Time and Neuronal Variability in Bipolar Disorder-A Combined Theoretical and Empirical Investigation. Schizophr Bull. 2018 01 13;44(1):54-64 Authors: Northoff G, Magioncalda P, Martino M, Lee HC, Tseng YC, Lane T Abstract Time is an essential feature in bipolar disorder (BP). Manic and depressed BP patients perceive the speed of time as either too fast or too slow. The present article combines theoretical and empirical approaches to integrate phenomenological, psychological, and neuroscientific accounts of abnormal time perception in BP. Phenomenology distinguishes between perception of inner time, ie, self-time, and outer time, ie, world-time, that ... read more
    Pubmed – tDCS and Cognition
  • The neural basis of induced phantom limb pain relief.
    Related ArticlesThe neural basis of induced phantom limb pain relief. Ann Neurol. 2018 Nov 01;: Authors: Kikkert S, Mezue M, O'Shea J, Henderson-Slater D, Johansen-Berg H, Tracey I, Makin TR Abstract OBJECTIVE: Phantom limb pain (PLP) is notoriously difficult to treat, partly due to an incomplete understanding of PLP-related disease mechanisms. Non-invasive brain stimulation (NIBS) is used to modulate plasticity in various neuropathological diseases, including chronic pain. While NIBS can alleviate neuropathic pain (including PLP), both disease and treatment mechanisms remain tenuous. Insight into the mechanisms underlying both PLP and NIBS-induced PLP relief is needed for future implementation of such ... read more
    Pubmed – tDCS and Cognition
  • Transcranial stimulation of the frontal lobes increases propensity of mind-wandering without changing meta-awareness.
    Related ArticlesTranscranial stimulation of the frontal lobes increases propensity of mind-wandering without changing meta-awareness. Sci Rep. 2018 Oct 29;8(1):15975 Authors: Axelrod V, Zhu X, Qiu J Abstract Mind-wandering is omnipresent in our lives. The benefits of mind-wandering are not yet clear, but given how much time we spend mind-wandering, this mental function is likely to be important. Accordingly, it is essential to understand the neural and cognitive mechanisms of mind-wandering. In a recent study by the leading author of the present paper it was demonstrated that by applying transcranial direct current stimulation (tDCS) of the frontal lobes, but not sham ... read more
    Pubmed – tDCS and Cognition
  • Neuromodulation treats Chikungunya arthralgia: a randomized controlled trial.
    Related ArticlesNeuromodulation treats Chikungunya arthralgia: a randomized controlled trial. Sci Rep. 2018 Oct 30;8(1):16010 Authors: Silva-Filho E, Okano AH, Morya E, Albuquerque J, Cacho E, Unal G, Bikson M, Pegado R Abstract The Chikungunya (CHIK) virus is epidemic in Brazil, with 170,000 cases in the first half of 2016. More than 60% of patients present relapsing and remitting chronic arthralgia with debilitating pain lasting years. There are no specific therapeutic agents to treat and rehabilitee infected persons with CHIK. Persistent pain can lead to incapacitation, requiring long-term pharmacological treatment. Advances in non-pharmacological treatments are necessary to promote pain relief without ... read more
    Pubmed – tDCS and Cognition
  • Would you be willing to zap your child’s brain? Public perspectives on parental responsibilities and the ethics of enhancing children with transcranial direct current stimulation.
    Related ArticlesWould you be willing to zap your child's brain? Public perspectives on parental responsibilities and the ethics of enhancing children with transcranial direct current stimulation. AJOB Empir Bioeth. 2018 Jan-Mar;9(1):29-38 Authors: Wagner K, Maslen H, Oakley J, Savulescu J Abstract BACKGROUND: Transcranial direct current stimulation (tDCS) is an experimental brain stimulation technology that may one day be used to enhance the cognitive capacities of children. Discussion about the ethical issues that this would raise has rarely moved beyond expert circles. However, the opinions of the wider public can lead to more democratic policy decisions and broaden academic discussion ... read more
    Pubmed – tDCS and Cognition
  • GABA, not BOLD, reveals dissociable learning-dependent plasticity mechanisms in the human brain.
    Related ArticlesGABA, not BOLD, reveals dissociable learning-dependent plasticity mechanisms in the human brain. Elife. 2018 Oct 25;7: Authors: Frangou P, Correia M, Kourtzi Z Abstract Experience and training have been shown to facilitate our ability to extract and discriminate meaningful patterns from cluttered environments. Yet, the human brain mechanisms that mediate our ability to learn by suppressing noisy and irrelevant signals remain largely unknown. To test the role of suppression in perceptual learning, we combine fMRI with MR Spectroscopy measurements of GABA, as fMRI alone does not allow us to discern inhibitory vs. excitatory mechanisms. Our results demonstrate that ... read more
    Pubmed – tDCS and Cognition
  • Transcranial direct current stimulation (tDCS) over right temporoparietal junction (rTPJ) for social cognition and social skills in adults with autism spectrum disorder (ASD).
    Related ArticlesTranscranial direct current stimulation (tDCS) over right temporoparietal junction (rTPJ) for social cognition and social skills in adults with autism spectrum disorder (ASD). J Neural Transm (Vienna). 2018 Oct 19;: Authors: Esse Wilson J, Trumbo MC, Wilson JK, Tesche CD Abstract Social deficits are core to autism spectrum disorder (ASD). Current treatments are extremely time- and labor-intensive. Transcranial direct current stimulation (tDCS) may be a promising treatment modality to safely enhance treatments targeting social cognition and social skills. This pilot study investigates the effectiveness of social skills treatment interventions paired with anodal tDCS for six adults 18-58 years with ... read more
    Pubmed – tDCS and Cognition
  • Investigating the Role of the Primary Motor Cortex in Musical Creativity: A Transcranial Direct Current Stimulation Study.
    Related ArticlesInvestigating the Role of the Primary Motor Cortex in Musical Creativity: A Transcranial Direct Current Stimulation Study. Front Psychol. 2018;9:1758 Authors: Anic A, Olsen KN, Thompson WF Abstract Neuroscientific research has revealed interconnected brain networks implicated in musical creativity, such as the executive control network, the default mode network, and premotor cortices. The present study employed brain stimulation to evaluate the role of the primary motor cortex (M1) in creative and technically fluent jazz piano improvisations. We implemented transcranial direct current stimulation (tDCS) to alter the neural activation patterns of the left hemispheric M1 whilst pianists performed improvisations with ... read more
    Pubmed – tDCS and Cognition
  • Effects of neuromodulation on cognitive performance in individuals exhibiting addictive behaviors: A systematic review.
    Related ArticlesEffects of neuromodulation on cognitive performance in individuals exhibiting addictive behaviors: A systematic review. Drug Alcohol Depend. 2018 Oct 03;192:338-351 Authors: Naish KR, Vedelago L, MacKillop J, Amlung M Abstract BACKGROUND: There is growing interest in non-invasive brain stimulation techniques as treatments for addictive disorders. While multiple reviews have examined the effects of neuromodulation on craving and consumption, there has been no review of how neuromodulation affects cognitive functioning in addiction. This systematic review examined studies of the cognitive effects of transcranial direct current stimulation (tDCS) and transcranial magnetic stimulation (TMS) in individuals exhibiting addictive behavior. METHODS: Articles ... read more
    Pubmed – tDCS and Cognition
  • Remotely Supervised Transcranial Direct Current Stimulation Increases the Benefit of At-Home Cognitive Training in Multiple Sclerosis.
    Related ArticlesRemotely Supervised Transcranial Direct Current Stimulation Increases the Benefit of At-Home Cognitive Training in Multiple Sclerosis. Neuromodulation. 2018 Jun;21(4):383-389 Authors: Charvet L, Shaw M, Dobbs B, Frontario A, Sherman K, Bikson M, Datta A, Krupp L, Zeinapour E, Kasschau M Abstract OBJECTIVE: To explore the efficacy of remotely-supervised transcranial direct current stimulation (RS-tDCS) paired with cognitive training (CT) exercise in participants with multiple sclerosis (MS). METHODS: In a feasibility study of RS-tDCS in MS, participants completed ten sessions of tDCS paired with CT (1.5 mA × 20 min, dorsolateral prefrontal cortex montage). RS-tDCS participants were compared to ... read more
    Pubmed – tDCS and Cognition
  • Beneficial effects of anodal transcranial direct current stimulation (tDCS) on spatial working memory in patients with schizophrenia.
    Related ArticlesBeneficial effects of anodal transcranial direct current stimulation (tDCS) on spatial working memory in patients with schizophrenia. Eur Neuropsychopharmacol. 2018 Oct 03;: Authors: Schwippel T, Papazova I, Strube W, Fallgatter AJ, Hasan A, Plewnia C Abstract Schizophrenia is a severe and often detrimental psychiatric disorder. The individual patients' level of functioning is essentially determined by cognitive, particularly working memory (WM), deficits that are critically linked to dysfunctional activity of the dorsolateral prefrontal cortex (dlPFC). Transcranial direct current stimulation (tDCS) can transiently modulate activity of the dlPFC and remote areas and has been shown to improve WM functions. It ... read more
    Pubmed – tDCS and Cognition
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