Brain Stimulation Journal Feed

  • Transcutaneous nerve stimulation via the tragus: are we really stimulating the vagus nerve?
    Research on transcutaneous vagus nerve stimulation (tVNS) is accumulating. Several studies now assessed whether stimulating the auricular branch of the vagus nerve (ABVN) affects cognitive, emotional and neurological processes, similarly to the invasive stimulation of the vagus nerve at the cervix. Currently, the main areas that are targeted during auricular stimulation are the cymba concha and the tragus [1]. Recently, Badran et al. [2] published an important study on the brain activation patterns associated with tragus stimulation, showing that tragus stimulation was associated with stronger activation in afferent vagal cerebral areas compared to sham stimulation. ... read more
    Brain Stimulation Journal FeedBy Andreas M. Burger, Bart Verkuil
  • Novel application of virtual reality in patient engagement for deep brain stimulation: A pilot study
    Deep brain stimulation (DBS) is an efficacious intervention for neurological and other disorders such as Parkinson's disease, essential tremor, and dystonia [1]. While the scope of DBS is broadening, standardized content for patient engagement is less established. Without identifiable structural pathology and small surgical targets, patients often supplement with personal research. Additionally, there is growing emphasis on patient satisfaction as an indicator of quality, with perception of therapy and overall experience serving a key component in surgical outcome [2,3]. ... read more
    Brain Stimulation Journal FeedBy Malie K. Collins, Victoria Y. Ding, Robyn L. Ball, Dana L. Dolce, Jaimie M. Henderson, Casey H. Halpern
  • Non-motor outcomes of subthalamic stimulation in Parkinson’s disease depend on location of active contacts
    Subthalamic nucleus (STN) deep brain stimulation (DBS) improves quality of life (QoL), motor, and non-motor symptoms (NMS) in Parkinson's disease (PD). Few studies have investigated the influence of the location of neurostimulation on NMS. ... read more
    Brain Stimulation Journal FeedBy Haidar Salimi Dafsari, Jan Niklas Petry-Schmelzer, K. Ray-Chaudhuri, Keyoumars Ashkan, Luca Weis, Till A. Dembek, Michael Samuel, Alexandra Rizos, Monty Silverdale, Michael T. Barbe, Gereon R. Fink, Julian Evans, Pablo Martinez-Martin, Angelo Antonini, Veerle Visser-Vandewalle, Lars Timmermann, EUROPAR, the IPMDS Non Motor PD Study Group
  • Short-interval and long-interval intracortical inhibition of TMS-evoked EEG potentials
    Inhibition in the human motor cortex can be probed by means of paired-pulse transcranial magnetic stimulation (ppTMS) at interstimulus intervals of 2–3 ms (short-interval intracortical inhibition, SICI) or ∼100 ms (long-interval intracortical inhibition, LICI). Conventionally, SICI and LICI are recorded as motor evoked potential (MEP) inhibition in the hand muscle. Pharmacological experiments indicate that they are mediated by GABAA and GABAB receptors, respectively.Objective/Hypothesis: SICI and LICI of TMS-evoked EEG potentials (TEPs) and their pharmacological properties have not been systematically studied. ... read more
    Brain Stimulation Journal FeedBy Isabella Premoli, Julia Király, Florian Müller-Dahlhaus, Carl M. Zipser, Pierre Rossini, Christoph Zrenner, Ulf Ziemann, Paolo Belardinelli