Scientific Studies on tDCS and Cognition

PubMed Logo

Scientific Studies Related to tDCS and Cognition

This collection of articles was sourced from PubMed.gov 

As of Dec. 11th, we found over 340 articles focusing on tDCS and Cognition.

  • No Evidence That Baseline Prefrontal Cortical Excitability (3T-MRS) Predicts the Effects of Prefrontal tDCS on WM Performance.
    Related ArticlesNo Evidence That Baseline Prefrontal Cortical Excitability (3T-MRS) Predicts the Effects of Prefrontal tDCS on WM Performance. Front Neurosci. 2018;12:481 Authors: Talsma LJ, Broekhuizen JA, Huisman J, Slagter HA Abstract Transcranial direct current stimulation (tDCS) over the left dorsolateral prefrontal cortex (lDLPFC) is a promising tool to enhance working memory (WM) in clinical as well as healthy populations. Yet, tDCS does not affect everyone similarly: whereas tDCS improves WM in most individuals, some individuals do not, or actually show detriments in WM performance after stimulation. One hypothesis that has been put forward to account for individual differences in ... read more
    Pubmed – tDCS and Cognition
  • Transcranial direct current stimulation combined with cognitive training for the treatment of Parkinson Disease: A randomized, placebo-controlled study.
    Related ArticlesTranscranial direct current stimulation combined with cognitive training for the treatment of Parkinson Disease: A randomized, placebo-controlled study. Brain Stimul. 2018 Jul 18;: Authors: Manenti R, Cotelli MS, Cobelli C, Gobbi E, Brambilla M, Rusich D, Alberici A, Padovani A, Borroni B, Cotelli M Abstract BACKGROUND: A number of non-motor symptoms occurs in Parkinson Disease (PD), cognitive decline and mood disturbances representing the most prevalent. Recent studies reported that cognitive training could potentially help to attenuate cognitive deficits in patients with PD and several researches demonstrated a beneficial effect of active transcranial Direct Current Stimulation (tDCS) over the left ... read more
    Pubmed – tDCS and Cognition
  • Transcranial Direct Current Stimulation to Assist Experienced Pistol Shooters in Gaining Even-Better Performance Scores.
    Related ArticlesTranscranial Direct Current Stimulation to Assist Experienced Pistol Shooters in Gaining Even-Better Performance Scores. Cerebellum. 2018 Jul 23;: Authors: Kamali AM, Nami M, Yahyavi SS, Saadi ZK, Mohammadi A Abstract Recently, brain stimulation has been considered as a promising method for the empowerment of athletes' performance. This study recruited 16 pistol shooters who were randomly assigned to two arms, including the control receiving no intervention and the experimental group receiving either sham or real transcranial direct current stimulation (tDCS), i.e., anodal stimulation and cathodal suppression over the cerebellar and dorsolateral prefrontal cortex (dlPFC) regions, respectively. Our outcome measures were ... read more
    Pubmed – tDCS and Cognition
  • Transcranial direct current stimulation (tDCS) facilitates overall visual search response times but does not interact with visual search task factors.
    Related ArticlesTranscranial direct current stimulation (tDCS) facilitates overall visual search response times but does not interact with visual search task factors. PLoS One. 2018;13(3):e0194640 Authors: Sung K, Gordon B Abstract Whether transcranial direct current stimulation (tDCS) affects mental functions, and how any such effects arise from its neural effects, continue to be debated. We investigated whether tDCS applied over the visual cortex (Oz) with a vertex (Cz) reference might affect response times (RTs) in a visual search task. We also examined whether any significant tDCS effects would interact with task factors (target presence, discrimination difficulty, and stimulus brightness) ... read more
    Pubmed – tDCS and Cognition
  • A Clinical Trial with Combined Transcranial Direct Current Stimulation and Attentional Bias Modification in Alcohol Dependent Patients.
    A Clinical Trial with Combined Transcranial Direct Current Stimulation and Attentional Bias Modification in Alcohol Dependent Patients. Alcohol Clin Exp Res. 2018 Jul 19;: Authors: den Uyl TE, Gladwin TE, Lindenmeyer J, Wiers RW Abstract BACKGROUND: Modifying attentional processes with attentional bias modification (ABM) might be a relevant add-on to treatment in addiction. This study investigated whether influencing cortical plasticity with transcranial direct current stimulation (tDCS) could increase training effects. TDCS could also help alcohol-dependent patients to overcome craving and reduce relapse, independent of training. These approaches were combined to investigate effects in the treatment of alcoholism. METHODS: Ninety-eight patients ... read more
    Pubmed – tDCS and Cognition
  • Concurrent exergaming and transcranial direct current stimulation to improve balance in people with Parkinson’s disease: study protocol for a randomised controlled trial.
    Related ArticlesConcurrent exergaming and transcranial direct current stimulation to improve balance in people with Parkinson's disease: study protocol for a randomised controlled trial. Trials. 2018 Jul 16;19(1):387 Authors: Harris DM, Rantalainen T, Muthalib M, Johnson L, Duckham RL, Smith ST, Daly RM, Teo WP Abstract BACKGROUND: People with Parkinson's disease (PD) commonly experience postural instability, resulting in poor balance and an increased risk of falls. Exercise-based video gaming (exergaming) is a form of physical training that is delivered through virtual reality technology to facilitate motor learning and is efficacious in improving balance in aged populations. In addition, studies have ... read more
    Pubmed – tDCS and Cognition
  • A clinical trial with combined transcranial direct current stimulation and alcohol approach bias retraining.
    Related ArticlesA clinical trial with combined transcranial direct current stimulation and alcohol approach bias retraining. Addict Biol. 2017 Nov;22(6):1632-1640 Authors: den Uyl TE, Gladwin TE, Rinck M, Lindenmeyer J, Wiers RW Abstract Two studies showed an improvement in clinical outcomes after alcohol approach bias retraining, a form of Cognitive Bias Modification (CBM). We investigated whether transcranial direct current stimulation (tDCS) could enhance effects of CBM. TDCS is a neuromodulation technique that can increase neuroplasticity and has previously been found to reduce craving. One hundred alcohol-dependent inpatients (91 used for analysis) were randomized into three experimental groups in a double-blind ... read more
    Pubmed – tDCS and Cognition
  • Obesity, Appetite, and the Prefrontal Cortex.
    Related ArticlesObesity, Appetite, and the Prefrontal Cortex. Curr Obes Rep. 2017 Dec;6(4):380-388 Authors: Gluck ME, Viswanath P, Stinson EJ Abstract PURPOSE OF REVIEW: Obesity is a chronic illness and its prevalence is growing worldwide and numerous factors play a role in the regulation of food intake. The prefrontal cortex (PFC) is involved in high-order executive function, regulation of limbic reward regions, and the inhibition of impulsive behaviors. Understanding the role of the PFC in the control of appetite regulation may contribute to a greater understanding of the etiology of obesity and could improve weight loss outcomes. RECENT FINDINGS: Neuroimaging ... read more
    Pubmed – tDCS and Cognition
  • Prefrontal Modulation of Visual Processing and Sustained Attention in Aging, a Transcranial Direct Current Stimulation-Electroencephalogram Coregistration Approach.
    Related ArticlesPrefrontal Modulation of Visual Processing and Sustained Attention in Aging, a Transcranial Direct Current Stimulation-Electroencephalogram Coregistration Approach. J Cogn Neurosci. 2018 Jul 13;:1-16 Authors: Brosnan MB, Arvaneh M, Harty S, Maguire T, O'Connell R, Robertson IH, Dockree PM Abstract The ability to sustain attention is integral to healthy cognition in aging. The right PFC (rPFC) is critical for maintaining high levels of attentional focus. Whether plasticity of this region can be harnessed to support sustained attention in older adults is unknown. We used transcranial direct current stimulation to increase cortical excitability of the rPFC, while monitoring behavioral and electrophysiological ... read more
    Pubmed – tDCS and Cognition
  • NMDA Receptor-Mediated Motor Cortex Plasticity After 20 Hz Transcranial Alternating Current Stimulation.
    Related ArticlesNMDA Receptor-Mediated Motor Cortex Plasticity After 20 Hz Transcranial Alternating Current Stimulation. Cereb Cortex. 2018 Jul 10;: Authors: Wischnewski M, Engelhardt M, Salehinejad MA, Schutter DJLG, Kuo MF, Nitsche MA Abstract Transcranial alternating current stimulation (tACS) has been shown to modulate neural oscillations and excitability levels in the primary motor cortex (M1). These effects can last for more than an hour and an involvement of N-methyl-d-aspartate receptor (NMDAR) mediated synaptic plasticity has been suggested. However, to date the cortical mechanisms underlying tACS after-effects have not been explored. Here, we applied 20 Hz beta tACS to M1 while participants ... read more
    Pubmed – tDCS and Cognition
  • Extended Multiple-Field High-Definition transcranial direct current stimulation (HD-tDCS) is well tolerated and safe in healthy adults.
    Related ArticlesExtended Multiple-Field High-Definition transcranial direct current stimulation (HD-tDCS) is well tolerated and safe in healthy adults. Restor Neurol Neurosci. 2017;35(6):631-642 Authors: Turski CA, Kessler-Jones A, Chow C, Hermann B, Hsu D, Jones J, Seeger SK, Chappell R, Boly M, Ikonomidou C Abstract BACKGROUND: High definition transcranial direct current stimulation (HD-tDCS) has been administered over single brain regions for small numbers of sessions. Safety, feasibility and tolerability of HD-tDCS over multiple brain regions, multiple daily stimulations and long periods are not established. OBJECTIVE: We studied safety, feasibility and tolerability of daily HD-tDCS over 2-4 brain regions for 20 ... read more
    Pubmed – tDCS and Cognition
  • Multi-Electrode Alpha tACS During Varying Background Tasks Fails to Modulate Subsequent Alpha Power.
    Related ArticlesMulti-Electrode Alpha tACS During Varying Background Tasks Fails to Modulate Subsequent Alpha Power. Front Neurosci. 2018;12:428 Authors: Fekete T, Nikolaev AR, De Knijf F, Zharikova A, van Leeuwen C Abstract Transcranial alternating-current stimulation (tACS) for entraining alpha activity holds potential for influencing mental function, both in laboratory and clinical settings. While initial results of alpha entrainment are promising, questions remain regarding its translational potential-namely if tACS alpha entrainment is sufficiently robust to context and to what extent it can be upscaled to multi-electrode arrangements needed to direct currents into precise brain loci. We set out to explore these questions ... read more
    Pubmed – tDCS and Cognition
  • Oxiracetam or fastigial nucleus stimulation reduces cognitive injury at high altitude.
    Related ArticlesOxiracetam or fastigial nucleus stimulation reduces cognitive injury at high altitude. Brain Behav. 2017 Oct;7(10):e00762 Authors: Hu S, Shi J, Xiong W, Li W, Fang L, Feng H Abstract BACKGROUND: Cognitive impairment is common in people travelling to high altitude. Oxiracetam and electrical stimulation of cerebellar fastigial nucleus may have beneficial impacts. This study was to investigate the effects of preconditioning with Oxiracetam or fastigial nucleus stimulation (FNS) on cognitive decline following the ascension to high altitude. METHODS: The study was conducted on 60 male military voluntary members who were divided into control group, Oxiracetam group, and ... read more
    Pubmed – tDCS and Cognition
  • Prefrontal TDCS attenuates medial prefrontal connectivity upon being criticized in individuals scoring high on perceived criticism.
    Related ArticlesPrefrontal TDCS attenuates medial prefrontal connectivity upon being criticized in individuals scoring high on perceived criticism. Brain Imaging Behav. 2018 Jul 04;: Authors: Dedoncker J, Vanderhasselt MA, Remue J, De Witte S, Wu GR, Hooley JM, De Raedt R, Baeken C Abstract The mechanisms by which transcranial direct current stimulation (tDCS) influences emotional processing - and whether this is related to individual vulnerability for psychopathology - are still poorly understood. The present study aimed to investigate if one prefrontal tDCS session modulates mood and neural functional connectivity after being exposed to negative information differently in individuals low or high ... read more
    Pubmed – tDCS and Cognition
  • Non-invasive brain stimulation to enhance cognitive rehabilitation after stroke.
    Non-invasive brain stimulation to enhance cognitive rehabilitation after stroke. Neurosci Lett. 2018 Jun 27;: Authors: Draaisma LR, Wessel MJ, Hummel FC Abstract Stroke is the main cause for long-term disability. Stroke symptoms cover various domains, e.g., motor, sensory, language, or other cognitive functions. In clinical practice and rehabilitation research, especially motor impairment attracts much attention. However, also cognitive impairments are common after stroke, effecting approximately two-thirds of stroke patients in the acute phase. Although 30% of stroke patients spontaneously recover from their cognitive impairments, large amounts of patients remain cognitively impaired. These patients have more problems reintegrating in personal and ... read more
    Pubmed – tDCS and Cognition
  • Anodal Transcranial Direct-Current Stimulation Over the Right Dorsolateral Prefrontal Cortex Influences Emotional Face Perception.
    Related ArticlesAnodal Transcranial Direct-Current Stimulation Over the Right Dorsolateral Prefrontal Cortex Influences Emotional Face Perception. Neurosci Bull. 2018 Jun 14;: Authors: Yang LC, Ren P, Ma YY Abstract The dorsolateral prefrontal cortex (DLPFC) is considered to play a crucial role in many high-level functions, such as cognitive control and emotional regulation. Many studies have reported that the DLPFC can be activated during the processing of emotional information in tasks requiring working memory. However, it is still not clear whether modulating the activity of the DLPFC influences emotional perception in a detection task. In the present study, using transcranial direct-current stimulation ... read more
    Pubmed – tDCS and Cognition
  • The effect of transcranial direct current stimulation of the prefrontal cortex on implicit self-esteem is mediated by rumination after criticism.
    Related ArticlesThe effect of transcranial direct current stimulation of the prefrontal cortex on implicit self-esteem is mediated by rumination after criticism. Behav Res Ther. 2017 Dec;99:138-146 Authors: De Raedt R, Remue J, Loeys T, Hooley JM, Baeken C Abstract It has been proposed that a crucial link between cognitive (i.e., self-schemas) and biological vulnerability is prefrontal control. This is because decreased control leads to impaired ability to inhibit ruminative thinking after the activation of negative self-schemas. However, current evidence is mainly correlational. In the current experimental study we tested whether the effect of neurostimulation of the dorsolateral prefrontal cortex ... read more
    Pubmed – tDCS and Cognition
  • Direct current stimulation of endothelial monolayers induces a transient and reversible increase in transport due to the electroosmotic effect.
    Related ArticlesDirect current stimulation of endothelial monolayers induces a transient and reversible increase in transport due to the electroosmotic effect. Sci Rep. 2018 Jun 18;8(1):9265 Authors: Cancel LM, Arias K, Bikson M, Tarbell JM Abstract We investigated the effects of direct current stimulation (DCS) on fluid and solute transport across endothelial cell (EC) monolayers in vitro. Our motivation was transcranial direct current stimulation (tDCS) that has been investigated for treatment of neuropsychiatric disorders, to enhance neurorehabilitation, and to change cognition in healthy subjects. The mechanisms underlying this diversity of applications remain under investigation. To address the possible role of blood-brain ... read more
    Pubmed – tDCS and Cognition
  • Cognitive Rehabilitation in Parkinson’s Disease: Is it Feasible?
    Related ArticlesCognitive Rehabilitation in Parkinson's Disease: Is it Feasible? Arch Clin Neuropsychol. 2017 Nov 01;32(7):840-860 Authors: Biundo R, Weis L, Fiorenzato E, Antonini A Abstract Parkinson's disease (PD) is a common neurodegenerative disorder, characterized by motor and non-motor symptoms. Dementia is one of the most relevant non-motor symptoms considering its functional affect on PD patients' activities of daily living and family members' wellbeing. Cognitive abnormalities in PD are heterogeneous and reliable biomarkers to detect patients at risk for dementia early on remain to be identified. Pharmacological treatments specifically for PD dementia and mild cognitive impairment are lacking, and alternative ... read more
    Pubmed – tDCS and Cognition
  • Transcranial Direct Current Stimulation, Symptomatology, and Cognition in Psychosis: A Qualitative Review.
    Related ArticlesTranscranial Direct Current Stimulation, Symptomatology, and Cognition in Psychosis: A Qualitative Review. Front Behav Neurosci. 2018;12:94 Authors: Gupta T, Kelley NJ, Pelletier-Baldelli A, Mittal VA Abstract Schizophrenia is a chronic, debilitating condition that affects approximately 1% of the population. Individuals diagnosed with schizophrenia typically exhibit positive (e.g., hallucinations) and negative symptoms (e.g., anhedonia) and impairments in cognitive function. Given the limitations of antipsychotic medication and psychotherapy in fully treating psychosis symptomatology, there has been increasing interest in other interventions such as transcranial direct current stimulation (tDCS). tDCS is a non-invasive neuromodulation technique, that is safe, cost-effective, and widely accessible. ... read more
    Pubmed – tDCS and Cognition
  • Role of the Prefrontal Cortex in Pain Processing.
    Related ArticlesRole of the Prefrontal Cortex in Pain Processing. Mol Neurobiol. 2018 Jun 06;: Authors: Ong WY, Stohler CS, Herr DR Abstract The prefrontal cortex (PFC) is not only important in executive functions, but also pain processing. The latter is dependent on its connections to other areas of the cerebral neocortex, hippocampus, periaqueductal gray (PAG), thalamus, amygdala, and basal nuclei. Changes in neurotransmitters, gene expression, glial cells, and neuroinflammation occur in the PFC during acute and chronic pain, that result in alterations to its structure, activity, and connectivity. The medial PFC (mPFC) could serve dual, opposing roles in pain: ... read more
    Pubmed – tDCS and Cognition
  • Neuronal and behavioral effects of multi-day brain stimulation and memory training.
    Related ArticlesNeuronal and behavioral effects of multi-day brain stimulation and memory training. Neurobiol Aging. 2018 Jan;61:245-254 Authors: Antonenko D, Külzow N, Sousa A, Prehn K, Grittner U, Flöel A Abstract Strategies for memory enhancement, especially for the older population, are of great scientific and public interest. Here, we aimed at investigating neuronal and behavioral effects of transcranial direct current stimulation (tDCS) paired with memory training. Young and older adults were trained on an object-location-memory task on 3 consecutive days with either anodal or sham tDCS. Recall performance was assessed immediately after training, 1 day and 1 month later, as well as ... read more
    Pubmed – tDCS and Cognition
  • Anodal tDCS over Primary Motor Cortex Provides No Advantage to Learning Motor Sequences via Observation.
    Related ArticlesAnodal tDCS over Primary Motor Cortex Provides No Advantage to Learning Motor Sequences via Observation. Neural Plast. 2018;2018:1237962 Authors: Apšvalka D, Ramsey R, Cross ES Abstract When learning a new motor skill, we benefit from watching others. It has been suggested that observation of others' actions can build a motor representation in the observer, and as such, physical and observational learning might share a similar neural basis. If physical and observational learning share a similar neural basis, then motor cortex stimulation during observational practice should similarly enhance learning by observation as it does through physical practice. Here, we ... read more
    Pubmed – tDCS and Cognition
  • Improvements in Attention and Decision-Making Following Combined Behavioral Training and Brain Stimulation.
    Related ArticlesImprovements in Attention and Decision-Making Following Combined Behavioral Training and Brain Stimulation. Cereb Cortex. 2017 Jul 01;27(7):3675-3682 Authors: Filmer HL, Varghese E, Hawkins GE, Mattingley JB, Dux PE Abstract In recent years there has been a significant commercial interest in 'brain training' - massed or spaced practice on a small set of tasks to boost cognitive performance. Recently, researchers have combined cognitive training regimes with brain stimulation to try and maximize training benefits, leading to task-specific cognitive enhancement. It remains unclear, however, whether the performance gains afforded by such regimes can transfer to untrained tasks, or how training ... read more
    Pubmed – tDCS and Cognition
  • Individual differences in learning correlate with modulation of brain activity induced by transcranial direct current stimulation.
    Related ArticlesIndividual differences in learning correlate with modulation of brain activity induced by transcranial direct current stimulation. PLoS One. 2018;13(5):e0197192 Authors: Falcone B, Wada A, Parasuraman R, Callan DE Abstract Transcranial direct current stimulation (tDCS) has been shown to enhance cognitive performance on a variety of tasks. It is hypothesized that tDCS enhances performance by affecting task related cortical excitability changes in networks underlying or connected to the site of stimulation facilitating long term potentiation. However, many recent studies have called into question the reliability and efficacy of tDCS to induce modulatory changes in brain activity. In this study, ... read more
    Pubmed – tDCS and Cognition