Scientific Studies on tDCS and Cognition

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Scientific Studies Related to tDCS and Cognition

This collection of articles was sourced from PubMed.gov 

As of Dec. 11th, we found over 340 articles focusing on tDCS and Cognition.

  • Guidelines for TMS/tES clinical services and research through the COVID-19 pandemic.
    Related ArticlesGuidelines for TMS/tES clinical services and research through the COVID-19 pandemic. Brain Stimul. 2020 Jul - Aug;13(4):1124-1149 Authors: Bikson M, Hanlon CA, Woods AJ, Gillick BT, Charvet L, Lamm C, Madeo G, Holczer A, Almeida J, Antal A, Ay MR, Baeken C, Blumberger DM, Campanella S, Camprodon JA, Christiansen L, Loo C, Crinion JT, Fitzgerald P, Gallimberti L, Ghobadi-Azbari P, Ghodratitoostani I, Grabner RH, Hartwigsen G, Hirata A, Kirton A, Knotkova H, Krupitsky E, Marangolo P, Nakamura-Palacios EM, Potok W, Praharaj SK, Ruff CC, Schlaug G, Siebner HR, Stagg CJ, Thielscher A, Wenderoth N, Yuan TF, ... read more
    Pubmed – tDCS and CognitionPublished on 2020-07-03
    19 hours ago
  • Effects of repetitive transcranial magnetic stimulation with different frequencies on post-stroke aphasia: A PRISMA-compliant meta-analysis.
    Related ArticlesEffects of repetitive transcranial magnetic stimulation with different frequencies on post-stroke aphasia: A PRISMA-compliant meta-analysis. Medicine (Baltimore). 2020 Jun 12;99(24):e20439 Authors: Li T, Zeng X, Lin L, Xian T, Chen Z Abstract BACKGROUNDS: Previous studies indicated inconsistent results for the treatment effect of repetitive transcranial magnetic stimulation (rTMS) on post-stroke aphasics. The study conducted a meta-analysis to evaluate whether the rTMS with different frequencies demonstrated any effect in patients with post-stroke aphasia. METHODS: Electronic databases (PubMed, Web of Science, Medline, EMBASE, and Google Scholar) were searched for articles published before July 2019. Statistical analyses were made using ... read more
    Pubmed – tDCS and CognitionPublished on 2020-07-01
    3 days ago
  • Interaction of task-related learning and transcranial direct current stimulation of the prefrontal cortex in modulating executive functions.
    Related ArticlesInteraction of task-related learning and transcranial direct current stimulation of the prefrontal cortex in modulating executive functions. Neuropsychologia. 2019 08;131:148-159 Authors: Fehring DJ, Illipparampil R, Acevedo N, Jaberzadeh S, Fitzgerald PB, Mansouri FA Abstract The effects of transcranial direct-current stimulation (tDCS) on cognitive functions, such as response inhibition, might be mediated through plastic changes within the prefrontal cortex. Previous studies have also confirmed learning-related plasticity in prefrontal neurocircuitry. The susceptibility of prefrontal neurocircuitry for tDCS-induced plastic changes and consequent behavioural modulations might depend on the level of learning in a particular task. Variabilities in the cognitive outcome of ... read more
    Pubmed – tDCS and CognitionPublished on 2020-07-01
    3 days ago
  • Evidence-based Umbrella Review of Cognitive Effects of Prefrontal tDCS.
    Related ArticlesEvidence-based Umbrella Review of Cognitive Effects of Prefrontal tDCS. Soc Cogn Affect Neurosci. 2020 Jun 24;: Authors: Farhat LC, Carvalho AF, Solmi M, Brunoni AR Abstract Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation approach which has been increasingly used as an investigational tool in neuroscience. In social and affective neuroscience research, the prefrontal cortex has been primarily targeted, since this brain region is critically involved in complex psychobiological processes subserving both 'hot' and 'cold' domains. Although several studies have suggested that prefrontal tDCS can enhance neuropsychological outcomes, meta-analyses have reported conflicting results. Therefore, we aimed to ... read more
    Pubmed – tDCS and CognitionPublished on 2020-06-25
    1 week ago
  • Effects of transcranial direct current stimulation on the cognitive control of negative stimuli in borderline personality disorder.
    Related ArticlesEffects of transcranial direct current stimulation on the cognitive control of negative stimuli in borderline personality disorder. Sci Rep. 2019 01 23;9(1):332 Authors: Schulze L, Grove M, Tamm S, Renneberg B, Roepke S Abstract Borderline personality disorder (BPD) is characterized by impairments in the cognitive control of negative information. These impairments in cognitive control are presumably due to blunted activity of the dorsolateral prefrontal cortex (dlPFC) along with enhanced activations of the limbic system. However, the impact of an excitatory stimulation of the dlPFC still needs to be elucidated. In the present study, we therefore assigned 50 ... read more
    Pubmed – tDCS and CognitionPublished on 2020-06-25
    1 week ago
  • Traumatic axonal injury influences the cognitive effect of non-invasive brain stimulation.
    Related ArticlesTraumatic axonal injury influences the cognitive effect of non-invasive brain stimulation. Brain. 2019 10 01;142(10):3280-3293 Authors: Li LM, Violante IR, Zimmerman K, Leech R, Hampshire A, Patel M, Opitz A, McArthur D, Jolly A, Carmichael DW, Sharp DJ Abstract Non-invasive brain stimulation has been widely investigated as a potential treatment for a range of neurological and psychiatric conditions, including brain injury. However, the behavioural effects of brain stimulation are variable, for reasons that are poorly understood. This is a particular challenge for traumatic brain injury, where patterns of damage and their clinical effects are heterogeneous. Here we ... read more
    Pubmed – tDCS and CognitionPublished on 2020-06-17
    2 weeks ago
  • Inferring Causality from Noninvasive Brain Stimulation in Cognitive Neuroscience.
    Related ArticlesInferring Causality from Noninvasive Brain Stimulation in Cognitive Neuroscience. J Cogn Neurosci. 2020 Jun 12;:1-29 Authors: Bergmann TO, Hartwigsen G Abstract Noninvasive brain stimulation (NIBS) techniques, such as transcranial magnetic stimulation or transcranial direct and alternating current stimulation, are advocated as measures to enable causal inference in cognitive neuroscience experiments. Transcending the limitations of purely correlative neuroimaging measures and experimental sensory stimulation, they allow to experimentally manipulate brain activity and study its consequences for perception, cognition, and eventually, behavior. Although this is true in principle, particular caution is advised when interpreting brain stimulation experiments in a causal manner. Research ... read more
    Pubmed – tDCS and CognitionPublished on 2020-06-13
    3 weeks ago
  • Transcranial Direct Current Stimulation (tDCS) Combined With Therapeutic Exercise in Chronic Low Back Pain: Protocol of a Randomized Controlled Trial.
    Related ArticlesTranscranial Direct Current Stimulation (tDCS) Combined With Therapeutic Exercise in Chronic Low Back Pain: Protocol of a Randomized Controlled Trial. Phys Ther. 2020 Jun 11;: Authors: Cavalcante PGL, Baptista AF, Cardoso VS, de Carvalho Filgueiras M, Hasue RH, João SMA, Hazime FA PMID: 32526017 [PubMed - as supplied by publisher] ... read more
    Pubmed – tDCS and CognitionPublished on 2020-06-12
    3 weeks ago
  • Non-invasive Brain Stimulation in Alzheimer’s Disease and Mild Cognitive Impairment-A State-of-the-Art Review on Methodological Characteristics and Stimulation Parameters.
    Related ArticlesNon-invasive Brain Stimulation in Alzheimer's Disease and Mild Cognitive Impairment-A State-of-the-Art Review on Methodological Characteristics and Stimulation Parameters. Front Hum Neurosci. 2020;14:179 Authors: Holczer A, Németh VL, Vékony T, Vécsei L, Klivényi P, Must A Abstract Background: Transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS) have been proposed as a new therapeutic way to enhance the cognition of patients with dementia. However, serious methodological limitations appear to affect the estimates of their efficacy. We reviewed the stimulation parameters and methods of studies that used TMS or tDCS to alleviate the cognitive symptoms of patients with Alzheimer's disease ... read more
    Pubmed – tDCS and CognitionPublished on 2020-06-12
    3 weeks ago
  • Impact of concurrent task performance on transcranial direct current stimulation (tDCS)-Induced changes in cortical physiology and working memory.
    Related ArticlesImpact of concurrent task performance on transcranial direct current stimulation (tDCS)-Induced changes in cortical physiology and working memory. Cortex. 2019 04;113:37-57 Authors: Hill AT, Rogasch NC, Fitzgerald PB, Hoy KE Abstract Transcranial direct current stimulation (tDCS) provides a means of non-invasively inducing plasticity-related changes in neural circuits in vivo and is experiencing increasing use as a potential tool for modulating brain function. There is growing evidence that tDCS-related outcomes are likely to be influenced by an individual's brain state at the time of stimulation, i.e., effects show a degree of 'state-dependency'. However, few studies have examined the behavioural and ... read more
    Pubmed – tDCS and CognitionPublished on 2020-06-09
    4 weeks ago
  • Behavioural and electrophysiological modulations induced by transcranial direct current stimulation in healthy elderly and Alzheimer’s disease patients: A pilot study.
    Related ArticlesBehavioural and electrophysiological modulations induced by transcranial direct current stimulation in healthy elderly and Alzheimer's disease patients: A pilot study. Clin Neurophysiol. 2019 11;130(11):2038-2052 Authors: Cespón J, Rodella C, Miniussi C, Pellicciari MC Abstract OBJECTIVE: To investigate whether anodal and cathodal transcranial direct current stimulation (tDCS) can modify cognitive performance and neural activity in healthy elderly and Alzheimer's disease (AD) patients. METHODS: Fourteen healthy elderly and twelve AD patients performed a working memory task during an electroencephalogram recording before and after receiving anodal, cathodal, and sham tDCS over the left dorsolateral prefrontal cortex. Behavioural performance, event-related potentials (P200, ... read more
    Pubmed – tDCS and CognitionPublished on 2020-06-09
    4 weeks ago
  • Offline effects of transcranial direct current stimulation on reaction times of lower extremity movements in people after stroke: a pilot cross-over study.
    Related ArticlesOffline effects of transcranial direct current stimulation on reaction times of lower extremity movements in people after stroke: a pilot cross-over study. J Neuroeng Rehabil. 2019 11 07;16(1):136 Authors: Coppens MJM, Staring WHA, Nonnekes J, Geurts ACH, Weerdesteyn V Abstract BACKGROUND: Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique that has shown promise for rehabilitation after stroke. Ipsilesional anodal tDCS (a-tDCS) over the motor cortex increases corticospinal excitability, while contralesional cathodal tDCS (c-tDCS) restores interhemispheric balance, both resulting in offline improved reaction times of delayed voluntary upper-extremity movements. We aimed to investigate whether tDCS ... read more
    Pubmed – tDCS and CognitionPublished on 2020-06-09
    4 weeks ago
  • Dopamine depletion effects on cognitive flexibility as modulated by tDCS of the dlPFC.
    Related ArticlesDopamine depletion effects on cognitive flexibility as modulated by tDCS of the dlPFC. Brain Stimul. 2020 Jan - Feb;13(1):105-108 Authors: Borwick C, Lal R, Lim LW, Stagg CJ, Aquili L Abstract BACKGROUND: Recent evidence suggests that transcranial direct current stimulation (tDCS) may interact with the dopaminergic system to affect cognitive flexibility. Objective/hypotheses: We examined whether putative reduction of dopamine levels through the acute phenylalanine/tyrosine depletion (APTD) procedure and excitatory anodal tDCS of the dorsolateral prefrontal cortex (dlPFC) are causally related to cognitive flexibility as measured by task switching and reversal learning. METHOD: A double-blind, sham-controlled, randomised trial ... read more
    Pubmed – tDCS and CognitionPublished on 2020-06-06
    4 weeks ago
  • Transcranial stimulation in frontotemporal dementia: A randomized, double-blind, sham-controlled trial.
    Related ArticlesTranscranial stimulation in frontotemporal dementia: A randomized, double-blind, sham-controlled trial. Alzheimers Dement (N Y). 2020;6(1):e12033 Authors: Benussi A, Dell'Era V, Cosseddu M, Cantoni V, Cotelli MS, Cotelli M, Manenti R, Benussi L, Brattini C, Alberici A, Borroni B Abstract Introduction: Frontotemporal dementia (FTD) is a progressive disease for which no curative treatment is currently available. We aimed to determine whether transcranial direct current stimulation (tDCS) can modulate intracortical connectivity and improve cognition in symptomatic FTD patients and presymptomatic FTD subjects. Methods: We performed a double-blind, randomized, sham-controlled trial with anodal tDCS or sham stimulation over the left prefrontal cortex ... read more
    Pubmed – tDCS and CognitionPublished on 2020-06-04
    4 weeks ago
  • Transcranial direct current stimulation and emotion processing deficits in psychosis and depression.
    Related ArticlesTranscranial direct current stimulation and emotion processing deficits in psychosis and depression. Eur Arch Psychiatry Clin Neurosci. 2020 Jun 01;: Authors: Gupta T, Mittal VA Abstract Emotional processing deficits (EPDs) are commonly observed among individuals diagnosed with (1) psychotic disorders (2) and depression. Given that EPDs can impact overall functioning and quality of life, the need to identify effective interventions is critical. To date, our current understanding of treatments for these impairments is limited. However, there is increasing interest in investigating the efficacy of transcranial direct current stimulation (tDCS). This neuromodulation technique releases a weak electrical current through the ... read more
    Pubmed – tDCS and CognitionPublished on 2020-06-04
    4 weeks ago
  • A New Approach to Transcranial Direct Current Stimulation in Improving Cognitive Motor Learning and Hand Function with the Nintendo Switch in Stroke Survivors.
    Related ArticlesA New Approach to Transcranial Direct Current Stimulation in Improving Cognitive Motor Learning and Hand Function with the Nintendo Switch in Stroke Survivors. Med Sci Monit. 2019 Dec 14;25:9555-9562 Authors: Kim J, Lee M, Yim J Abstract BACKGROUND Transcranial direct current stimulation (tDCS) is a noninvasive brain stimulation (NIBS) technique designed to improve cognitive and physical function of stroke survivors. There are many studies being conducted in the search for an effective intervention of tDCS. This study focused on cognitive motor learning in relation to hand function of stroke survivors. MATERIAL AND METHODS We enrolled 30 subjects with ... read more
    Pubmed – tDCS and CognitionPublished on 2020-06-04
    4 weeks ago
  • Feasibility of Computerized Cognitive-Behavioral Therapy Combined With Bifrontal Transcranial Direct Current Stimulation for Treatment of Major Depression.
    Related ArticlesFeasibility of Computerized Cognitive-Behavioral Therapy Combined With Bifrontal Transcranial Direct Current Stimulation for Treatment of Major Depression. Neuromodulation. 2019 Dec;22(8):898-903 Authors: Welch ES, Weigand A, Hooker JE, Philip NS, Tyrka AR, Press DZ, Carpenter LL Abstract BACKGROUND: Cognitive behavioral therapy (CBT) is effective in the treatment of major depressive disorder (MDD). Transcranial Direct Current Stimulation (tDCS) has demonstrated preliminary antidepressant effects and beneficial effects on cognitive function. OBJECTIVE: We investigated the feasibility and acceptability of using tDCS to enhance the effects of computer-based CBT for treatment of MDD. MATERIALS AND METHODS: In a randomized, double-blind, sham-controlled study, 14 ... read more
    Pubmed – tDCS and CognitionPublished on 2020-06-02
    1 month ago
  • Brain state and polarity dependent modulation of brain networks by transcranial direct current stimulation.
    Related ArticlesBrain state and polarity dependent modulation of brain networks by transcranial direct current stimulation. Hum Brain Mapp. 2019 02 15;40(3):904-915 Authors: Li LM, Violante IR, Leech R, Ross E, Hampshire A, Opitz A, Rothwell JC, Carmichael DW, Sharp DJ Abstract Despite its widespread use in cognitive studies, there is still limited understanding of whether and how transcranial direct current stimulation (tDCS) modulates brain network function. To clarify its physiological effects, we assessed brain network function using functional magnetic resonance imaging (fMRI) simultaneously acquired during tDCS stimulation. Cognitive state was manipulated by having subjects perform a Choice Reaction ... read more
    Pubmed – tDCS and CognitionPublished on 2020-05-28
    1 month ago
  • Localized Analysis of Normalized Distance from Scalp to Cortex and Personalized Evaluation (LANDSCAPE): Focusing on Age- and Dementia-Specific Changes.
    Related ArticlesLocalized Analysis of Normalized Distance from Scalp to Cortex and Personalized Evaluation (LANDSCAPE): Focusing on Age- and Dementia-Specific Changes. J Alzheimers Dis. 2019;67(4):1331-1341 Authors: Lu H, Chan SSM, Lam LCW Abstract BACKGROUND: Scalp to cortex distance (SCD), as a key technological parameter, has been highlighted in the guidelines of non-invasive brain stimulation. However, in the context of age-related brain changes, the region-specific SCD and its impact on stimulation-induced electric field remain unclear. OBJECTIVE: This study aimed to investigate the region-specific SCD and its relationship with morphometric features and cognitive function in age- and disease-specific populations. METHODS: We analyzed ... read more
    Pubmed – tDCS and CognitionPublished on 2020-05-28
    1 month ago
  • The COMT Val158 Met polymorphism does not modulate the after-effect of tDCS on working memory.
    Related ArticlesThe COMT Val158 Met polymorphism does not modulate the after-effect of tDCS on working memory. Eur J Neurosci. 2019 01;49(2):263-274 Authors: Jongkees BJ, Loseva AA, Yavari FB, Nitsche MA, Colzato LS Abstract Transcranial direct current stimulation (tDCS) can alter cortical excitability, neural plasticity, and cognitive-behavioral performance; however, its effects are known to vary across studies. A partial account of this variability relates to individual differences in dopamine function. Indeed, dopaminergic manipulations alter the physiological and cognitive-behavioral effects of tDCS, and gene polymorphisms related to dopamine have predicted individual response to online tDCS (i.e., stimulation overlapping with the ... read more
    Pubmed – tDCS and CognitionPublished on 2020-05-27
    1 month ago
  • Increased thalamocortical connectivity to the medial prefrontal cortex with recovery of impaired consciousness in a stroke patient: A case report.
    Related ArticlesIncreased thalamocortical connectivity to the medial prefrontal cortex with recovery of impaired consciousness in a stroke patient: A case report. Medicine (Baltimore). 2020 May;99(18):e19937 Authors: Jang SH, Seo YS, Lee SJ Abstract RATIONALE: We report a stroke patient who showed increased thalamocortical connectivity to the medial prefrontal cortex (mPFC) with recovery of impaired consciousness that was demonstrated on diffusion tensor tractography (DTT) of the ascending reticular activating system (ARAS). PATIENTS CONCERNS: A 48-year-old male patient underwent craniectomy and hematoma removal for spontaneous intracerebral hemorrhage in the right basal ganglia and thalamus. When he started rehabilitation at 5 weeks ... read more
    Pubmed – tDCS and CognitionPublished on 2020-05-27
    1 month ago
  • Optimising Cognitive Enhancement: Systematic Assessment of the Effects of tDCS Duration in Older Adults.
    Optimising Cognitive Enhancement: Systematic Assessment of the Effects of tDCS Duration in Older Adults. Brain Sci. 2020 May 16;10(5): Authors: Hanley CJ, Alderman SL, Clemence E Abstract Transcranial direct current stimulation (tDCS) has been shown to support cognition and brain function in older adults. However, there is an absence of research specifically designed to determine optimal stimulation protocols, and much of what is known about subtle distinctions in tDCS parameters is based on young adult data. As the first systematic exploration targeting older adults, this study aimed to provide insight into the effects of variations in stimulation duration. Anodal stimulation ... read more
    Pubmed – tDCS and CognitionPublished on 2020-05-21
    1 month ago
  • Boosting Slow Oscillations during Sleep to Improve Memory Function in Elderly People: A Review of the Literature.
    Boosting Slow Oscillations during Sleep to Improve Memory Function in Elderly People: A Review of the Literature. Brain Sci. 2020 May 15;10(5): Authors: Salfi F, D'Atri A, Tempesta D, De Gennaro L, Ferrara M Abstract Sleep represents a crucial time window for the consolidation of memory traces. In this view, some brain rhythms play a pivotal role, first of all the sleep slow waves. In particular, the neocortical slow oscillations (SOs), in coordination with the hippocampal ripples and the thalamocortical spindles, support the long-term storage of the declarative memories. The aging brain is characterized by a disruption of this complex ... read more
    Pubmed – tDCS and CognitionPublished on 2020-05-21
    1 month ago
  • Prognostic and Monitory EEG-Biomarkers for BCI Upper-Limb Stroke Rehabilitation.
    Related ArticlesPrognostic and Monitory EEG-Biomarkers for BCI Upper-Limb Stroke Rehabilitation. IEEE Trans Neural Syst Rehabil Eng. 2019 08;27(8):1654-1664 Authors: Mane R, Chew E, Phua KS, Ang KK, Robinson N, Vinod AP, Guan C Abstract With the availability of multiple rehabilitative interventions, identifying the one that elicits the best motor outcome based on the unique neuro-clinical profile of the stroke survivor is a challenging task. Predicting the potential of recovery using biomarkers specific to an intervention hence becomes important. To address this, we investigate intervention-specific prognostic and monitory biomarkers of motor function improvements using quantitative electroencephalography (QEEG) features in 19 ... read more
    Pubmed – tDCS and CognitionPublished on 2020-05-19
    2 months ago
  • Does Transcranial Direct Current Stimulation Affect the Learning of a Fine Sequential Hand Motor Skill with Motor Imagery?
    Related ArticlesDoes Transcranial Direct Current Stimulation Affect the Learning of a Fine Sequential Hand Motor Skill with Motor Imagery? J Mot Behav. 2019;51(4):451-465 Authors: Sobierajewicz J, Jaśkowski W, Van der Lubbe RHJ Abstract Learning a fine sequential hand motor skill, like playing the piano or learning to type, improves not only due to physical practice, but also due to motor imagery. Previous studies revealed that transcranial direct current stimulation (tDCS) and motor imagery independently affect motor learning. In the present study, we investigated whether tDCS combined with motor imagery above the primary motor cortex influences sequence-specific learning. Four groups of ... read more
    Pubmed – tDCS and CognitionPublished on 2020-05-15
    2 months ago