Scientific Studies on tDCS and Cognition

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Scientific Studies Related to tDCS and Cognition

This collection of articles was sourced from PubMed.gov 

As of Dec. 11th, we found over 340 articles focusing on tDCS and Cognition.

  • Differential effects of transcranial direct current stimulation on antiphase and inphase motor tasks: A pilot study.
    Related ArticlesDifferential effects of transcranial direct current stimulation on antiphase and inphase motor tasks: A pilot study. Behav Brain Res. 2019 07 02;366:13-18 Authors: Ryan K, Schranz AL, Duggal N, Bartha R Abstract Ageing is associated with a decline in motor function that critically interferes with activities of daily living involving manual dexterity. Transcranial direct current stimulation (tDCS) is a form of non-invasive brain stimulation that has been shown to enhance manual dexterity in healthy aging adults. The supplementary motor area (SMA) is involved in motor preparation and bimanual control; therefore, bihemispheric tDCS incorporating the SMA may preferentially enhance ... read more
    Pubmed – tDCS and CognitionPublished on 2020-03-28
    1 week ago
  • Cognitive Impairment and Brain Reorganization in MS: Underlying Mechanisms and the Role of Neurorehabilitation.
    Related ArticlesCognitive Impairment and Brain Reorganization in MS: Underlying Mechanisms and the Role of Neurorehabilitation. Front Neurol. 2020;11:147 Authors: Nasios G, Bakirtzis C, Messinis L Abstract Multiple sclerosis (MS) is a chronic, immune-mediated, inflammatory, and degenerative disease of the central nervous system (CNS) that affects both white and gray matter. Various mechanisms throughout its course, mainly regarding gray matter lesions and brain atrophy, result in cognitive network dysfunction and can cause clinically significant cognitive impairment in roughly half the persons living with MS. Altered cognition is responsible for many negative aspects of patients' lives, independently of physical disability, such as ... read more
    Pubmed – tDCS and CognitionPublished on 2020-03-28
    1 week ago
  • The immediate and delayed effects of single tDCS session over posterior parietal cortex on face-word associative memory.
    Related ArticlesThe immediate and delayed effects of single tDCS session over posterior parietal cortex on face-word associative memory. Behav Brain Res. 2019 07 02;366:88-95 Authors: Bjekić J, Vulić K, Živanović M, Vujičić J, Ljubisavljević M, Filipović SR Abstract Associative memory (AM), an ability to form and retrieve associations between information units is crucial for everyday functioning and is affected by aging as well as by different neurological conditions. It was shown that rTMS over posterior parietal cortex (PPC) can improve AM of face-word pairs. Therefore, we examined if tDCS will produce comparable effects and explore whether the effect would ... read more
    Pubmed – tDCS and CognitionPublished on 2020-03-28
    1 week ago
  • Neural predictors of treatment response to brain stimulation and psychological therapy in depression: a double-blind randomized controlled trial.
    Related ArticlesNeural predictors of treatment response to brain stimulation and psychological therapy in depression: a double-blind randomized controlled trial. Neuropsychopharmacology. 2019 08;44(9):1613-1622 Authors: Nord CL, Halahakoon DC, Limbachya T, Charpentier C, Lally N, Walsh V, Leibowitz J, Pilling S, Roiser JP Abstract Standard depression treatments, including antidepressant medication and cognitive behavioural therapy (CBT), are ineffective for many patients. Prefrontal transcranial direct current stimulation (tDCS) has been proposed as an alternative treatment, but has shown inconsistent efficacy for depression, and its mechanisms are poorly understood. We recruited unmedicated patients with major depressive disorder (N = 71 approached; N = 39 randomised) for a mechanistic, double-blind, ... read more
    Pubmed – tDCS and CognitionPublished on 2020-03-18
    3 weeks ago
  • Noninvasive brain stimulation for behavioural and psychological symptoms of dementia: A systematic review and meta-analysis.
    Related ArticlesNoninvasive brain stimulation for behavioural and psychological symptoms of dementia: A systematic review and meta-analysis. Int J Geriatr Psychiatry. 2019 09;34(9):1336-1345 Authors: Vacas SM, Stella F, Loureiro JC, Simões do Couto F, Oliveira-Maia AJ, Forlenza OV Abstract BACKGROUND: Pharmacological and conventional nonpharmacological treatments for behavioural and psychological symptoms of dementia (BPSD) have only modest efficacy. Furthermore, pharmacotherapy carries the risk of important side effects. Noninvasive brain stimulation (repetitive transcranial magnetic stimulation (TMS) or transcranial direct current stimulation (tDCS)) are valuable and safe for cognitive function in Alzheimer disease (AD). However, there have been few studies, and there is ... read more
    Pubmed – tDCS and CognitionPublished on 2020-03-14
    3 weeks ago
  • Left Prefrontal Cortex Supports the Recognition of Meaningful Patterns in Ambiguous Stimuli.
    Related ArticlesLeft Prefrontal Cortex Supports the Recognition of Meaningful Patterns in Ambiguous Stimuli. Front Neurosci. 2020;14:152 Authors: Bartel G, Marko M, Rameses I, Lamm C, Riečanský I Abstract Processing of ambiguous visual stimuli has been associated with an increased activation of the left lateral prefrontal cortex (PFC) in neuroimaging studies. Nevertheless, the functional role of prefrontal activity in this process is not fully understood. In this experiment we asked participants to evaluate ambiguous inkblots from the Rorschach test, while stimulating the left lateral PFC using excitatory anodal transcranial direct current stimulation (tDCS). In addition, visual insight ability was assessed as ... read more
    Pubmed – tDCS and CognitionPublished on 2020-03-11
    4 weeks ago
  • Transcranial direct current stimulation to enhance athletic performance outcome in experienced bodybuilders.
    Related ArticlesTranscranial direct current stimulation to enhance athletic performance outcome in experienced bodybuilders. PLoS One. 2019;14(8):e0220363 Authors: Kamali AM, Saadi ZK, Yahyavi SS, Zarifkar A, Aligholi H, Nami M Abstract Transcranial direct current stimulation (tDCS) is currently under investigation as a promising technique for enhancement of athletic performance through modulating cortical excitability. Through consecutive randomization, 12 experienced bodybuilders were randomly assigned to two arms receiving either sham or real tDCS over the primary motor cortex (leg area) and left temporal cortex (T3) for 13 minutes in the first session. After 72 hours, both groups received the inverse stimulation. ... read more
    Pubmed – tDCS and CognitionPublished on 2020-03-10
    4 weeks ago
  • Prefrontal Cortex Neuromodulation Enhances Frontal Asymmetry and Reduces Caloric Intake in Patients with Morbid Obesity.
    Related ArticlesPrefrontal Cortex Neuromodulation Enhances Frontal Asymmetry and Reduces Caloric Intake in Patients with Morbid Obesity. Obesity (Silver Spring). 2020 Mar 06;: Authors: Forcano L, Castellano M, Cuenca-Royo A, Goday-Arno A, Pastor A, Langohr K, Castañer O, Pérez-Vega KA, Serra C, Ruffini G, Alonso-Alonso M, Soria-Frisch A, de la Torre R Abstract OBJECTIVE: The objective of this study was to test the feasibility of a combined intervention involving transcranial direct current stimulation (tDCS) on the dorsolateral prefrontal cortex (dlPFC) and cognitive training (CT). Short-term effects on food consumption, cognition, endocannabinoid (eCB) levels, and electroencephalogram (EEG) markers of future weight loss were ... read more
    Pubmed – tDCS and CognitionPublished on 2020-03-08
    4 weeks ago
  • Differential effects of left and right prefrontal cortex anodal transcranial direct current stimulation during probabilistic sequence learning.
    Related ArticlesDifferential effects of left and right prefrontal cortex anodal transcranial direct current stimulation during probabilistic sequence learning. J Neurophysiol. 2019 05 01;121(5):1906-1916 Authors: Greeley B, Seidler RD Abstract Left and right prefrontal cortex and the primary motor cortex (M1) are activated during learning of motor sequences. Previous literature is mixed on whether prefrontal cortex aids or interferes with sequence learning. The present study investigated the roles of prefrontal cortices and M1 in sequence learning. Participants received anodal transcranial direct current stimulation (tDCS) to right or left prefrontal cortex or left M1 during a probabilistic sequence learning task. Relative ... read more
    Pubmed – tDCS and CognitionPublished on 2020-02-27
    1 month ago
  • Improved conceptual generation and selection with transcranial direct current stimulation in older adults.
    Related ArticlesImproved conceptual generation and selection with transcranial direct current stimulation in older adults. J Clin Exp Neuropsychol. 2019 02;41(1):43-57 Authors: Madden DL, Sale MV, Robinson GA Abstract INTRODUCTION: Normal aging is associated with deficits in various aspects of spoken language production, including idea generation and selection, and involves activity in frontal brain areas including left inferior frontal cortex (LIFG). These conceptual preparation processes, largely involving executive control, precede formulation and articulation stages and are critical for language production. Noninvasive brain stimulation (e.g., transcranial direct current stimulation, tDCS) has proven beneficial for age-related fluency and naming deficits, but this has ... read more
    Pubmed – tDCS and CognitionPublished on 2020-02-26
    1 month ago
  • Effects of beta-tACS on corticospinal excitability: A meta-analysis.
    Related ArticlesEffects of beta-tACS on corticospinal excitability: A meta-analysis. Brain Stimul. 2019 Nov - Dec;12(6):1381-1389 Authors: Wischnewski M, Schutter DJLG, Nitsche MA Abstract Over the past decade several studies have shown that transcranial alternating current stimulation (tACS) delivered at the beta (15-25 Hz) frequency range can increase corticospinal excitability of the primary motor cortex (M1). The aim of this study was to systematically quantify the effect size of beta-tACS on corticospinal excitability in healthy volunteers, as well as to identify significant outcome predictors. A meta-analysis was performed on the results of 47 experiments reported in 21 studies. Random effects ... read more
    Pubmed – tDCS and CognitionPublished on 2020-02-25
    1 month ago
  • After-effects of 10 Hz tACS over the prefrontal cortex on phonological word decisions.
    Related ArticlesAfter-effects of 10 Hz tACS over the prefrontal cortex on phonological word decisions. Brain Stimul. 2019 Nov - Dec;12(6):1464-1474 Authors: Moliadze V, Sierau L, Lyzhko E, Stenner T, Werchowski M, Siniatchkin M, Hartwigsen G Abstract INTRODUCTION: Previous work in the language domain has shown that 10 Hz rTMS of the left or right posterior inferior frontal gyrus (pIFG) in the prefrontal cortex impaired phonological decision-making, arguing for a causal contribution of the bilateral pIFG to phonological processing. However, the neurophysiological correlates of these effects are unclear. The present study addressed the question whether neural activity in the prefrontal cortex ... read more
    Pubmed – tDCS and CognitionPublished on 2020-02-25
    1 month ago
  • Potential impact of bifrontal transcranial random noise stimulation (tRNS) on the semantic Stroop effect and its resting-state EEG correlates.
    Related ArticlesPotential impact of bifrontal transcranial random noise stimulation (tRNS) on the semantic Stroop effect and its resting-state EEG correlates. Neurophysiol Clin. 2019 Jun;49(3):243-248 Authors: Dondé C, Brevet-Aeby C, Poulet E, Mondino M, Brunelin J Abstract OBJECTIVE: The Stroop effect performance reflects cognitive resistance to interference. We aimed to investigate the effect of a single transcranial random noise stimulation session (tRNS) applied over the dorsolateral prefrontal cortex (DLPFC) on the semantic Stroop effect and its resting electroencephalography (EEG) correlates (β/α ratio). METHODS: In a randomized, double-blind study, healthy volunteers were allocated to receive either one session of active tRNS ... read more
    Pubmed – tDCS and CognitionPublished on 2020-02-19
    2 months ago
  • Inverse effects of tDCS over the left versus right DLPC on emotional processing: A pupillometry study.
    Related ArticlesInverse effects of tDCS over the left versus right DLPC on emotional processing: A pupillometry study. PLoS One. 2019;14(6):e0218327 Authors: Allaert J, Sanchez-Lopez A, De Raedt R, Baeken C, Vanderhasselt MA Abstract BACKGROUND AND OBJECTIVES: The Dorsolateral prefrontal cortex (DLPFC) is implicated in cognitive and emotional responses. Yet, research that investigates the causal role of the left versus right DLPFC during the processes of emotion appraisal is lacking. In the current study, transcranial direct current stimulation (tDCS) was used to disentangle the functional lateralization of the DLPFC on emotional processing in response to the anticipation of, and ... read more
    Pubmed – tDCS and CognitionPublished on 2020-02-14
    2 months ago
  • A pilot study investigating the effect of transcranial direct current stimulation on the electrophysiological correlates of working memory in patients with schizophrenia.
    Related ArticlesA pilot study investigating the effect of transcranial direct current stimulation on the electrophysiological correlates of working memory in patients with schizophrenia. Psychiatry Res Neuroimaging. 2019 02 28;284:9-12 Authors: Moon SY, Kim M, Hwang WJ, Lee TY, Kwon JS Abstract Transcranial direct current stimulation (tDCS) exerts pro-cognitive effects in various populations. We evaluated the effect of tDCS on cognitive performance and its electrophysiological correlates in schizophrenia patients. Ten participants received 10 sessions of tDCS and performed cognitive performance tasks; error-related negativity and correct response negativity (CRN) were measured before and after tDCS. Verbal performance was improved by tDCS ... read more
    Pubmed – tDCS and CognitionPublished on 2020-02-07
    2 months ago
  • Unilateral Spatial Neglect After Stroke: Current Insights.
    Related ArticlesUnilateral Spatial Neglect After Stroke: Current Insights. Neuropsychiatr Dis Treat. 2020;16:131-152 Authors: Gammeri R, Iacono C, Ricci R, Salatino A Abstract Introduction: Unilateral spatial neglect (USN) is a disorder of contralesional space awareness which often follows unilateral brain lesion. Since USN impairs awareness of contralesional space/body and often of concomitant motor disorders, its presence represents a negative prognostic factor of functional recovery. Thus, the disorder needs to be carefully diagnosed and treated. Here, we attempted to present a clear and concise picture of current insights in the comprehension and rehabilitation of USN. Methods: We first provided an updated overview ... read more
    Pubmed – tDCS and CognitionPublished on 2020-02-06
    2 months ago
  • Testing the role of cognitive inhibition in physical endurance using high-definition transcranial direct current stimulation over the prefrontal cortex.
    Related ArticlesTesting the role of cognitive inhibition in physical endurance using high-definition transcranial direct current stimulation over the prefrontal cortex. Hum Mov Sci. 2019 Oct;67:102507 Authors: Denis G, Zory R, Radel R Abstract The aim of this study was to clarify the role of the prefrontal cortex (PFC) in physical effort regulation. We hypothesized that the PFC would be progressively involved in physical endurance through the engagement of cognitive inhibition, which would be necessary to maintain effort by inhibiting fatigue-related cues. This hypothesis was examined using a double-blind, sham-controlled, within-subjects study (N = 20) using high-definition (HD) transcranial direct current stimulation ... read more
    Pubmed – tDCS and CognitionPublished on 2020-01-21
    2 months ago
  • Electrophysiological modulation and cognitive-verbal enhancement by multi-session Broca’s stimulation: a quantitative EEG transcranial direct current stimulation based investigation.
    Related ArticlesElectrophysiological modulation and cognitive-verbal enhancement by multi-session Broca's stimulation: a quantitative EEG transcranial direct current stimulation based investigation. J Integr Neurosci. 2019 06 30;18(2):107-115 Authors: Saadi ZK, Saadat M, Kamali AM, Yahyavi SS, Nami M Abstract To evaluate transcranial direct current stimulation-induced changes in resting state quantitative EEG and cognitive-verbal performance of second language learners, 16 healthy individuals were randomly recruited to sham and real transcranial direct current stimulation groups receiving eight sessions of second language instruction accompanied by a 2 mA transcranial direct current stimulation over Broca's area with the cathode placed over the left arm. Quantitative ... read more
    Pubmed – tDCS and CognitionPublished on 2020-01-16
    3 months ago
  • Transcranial direct current stimulation for the treatment of major depressive disorder: A meta-analysis of randomized controlled trials.
    Related ArticlesTranscranial direct current stimulation for the treatment of major depressive disorder: A meta-analysis of randomized controlled trials. Psychiatry Res. 2019 06;276:186-190 Authors: Wang Y Abstract Major depressive disorder (MDD) is a common and refractory mental disorder. Although antidepressant drugs may be effective for treating MDD, a number of patients do not improve with pharmacologic treatment. Novel therapeutic strategies which are safer and more effective are of great significance in the treatment of MDD. Transcranial direct cranial stimulation (tDCS) is a promising intervention for treating MDD, and it has demonstrated antidepressant effects and beneficial effects on cognitive function. The ... read more
    Pubmed – tDCS and CognitionPublished on 2020-01-15
    3 months ago
  • Modulation of large-scale cortical coupling by transcranial alternating current stimulation.
    Related ArticlesModulation of large-scale cortical coupling by transcranial alternating current stimulation. Brain Stimul. 2019 Sep - Oct;12(5):1187-1196 Authors: Schwab BC, Misselhorn J, Engel AK Abstract BACKGROUND: Long-range functional connectivity in the brain is considered fundamental for cognition and is known to be altered in many neuropsychiatric disorders. To modify such coupling independent of sensory input, noninvasive brain stimulation could be of utmost value. OBJECTIVE: First, we tested if transcranial alternating current stimulation (tACS) is able to influence functional connectivity in the human brain. Second, we investigated the specificity of effects in frequency and space. METHODS: Participants were stimulated bifocally ... read more
    Pubmed – tDCS and CognitionPublished on 2020-01-14
    3 months ago
  • The Effect of Cerebellar tDCS on Sequential Motor Response Selection.
    Related ArticlesThe Effect of Cerebellar tDCS on Sequential Motor Response Selection. Cerebellum. 2019 Aug;18(4):738-749 Authors: Jongkees BJ, Immink MA, Boer OD, Yavari F, Nitsche MA, Colzato LS Abstract Transcranial direct current stimulation (tDCS) transiently alters cortical excitability and synaptic plasticity. So far, few studies have investigated the behavioral effects of applying tDCS to the cerebellum. Given the cerebellum's inhibitory effects on cortical motor areas as well as its role in fine motor control and motor coordination, we investigated whether cerebellar tDCS can modulate response selection processes and motor sequence learning. Seventy-two participants received either cerebellar anodal (excitatory), cathodal ... read more
    Pubmed – tDCS and CognitionPublished on 2020-01-14
    3 months ago
  • Prefrontal TDCS attenuates medial prefrontal connectivity upon being criticized in individuals scoring high on perceived criticism.
    Related ArticlesPrefrontal TDCS attenuates medial prefrontal connectivity upon being criticized in individuals scoring high on perceived criticism. Brain Imaging Behav. 2019 Aug;13(4):1060-1070 Authors: Dedoncker J, Vanderhasselt MA, Remue J, De Witte S, Wu GR, Hooley JM, De Raedt R, Baeken C Abstract The mechanisms by which transcranial direct current stimulation (tDCS) influences emotional processing - and whether this is related to individual vulnerability for psychopathology - are still poorly understood. The present study aimed to investigate if one prefrontal tDCS session modulates mood and neural functional connectivity after being exposed to negative information differently in individuals low or high ... read more
    Pubmed – tDCS and CognitionPublished on 2020-01-08
    3 months ago
  • Stimulation Location Determination using a 3D Digitizer with High-Definition Transcranial Direct Current Stimulation.
    Stimulation Location Determination using a 3D Digitizer with High-Definition Transcranial Direct Current Stimulation. J Vis Exp. 2019 Dec 20;(154): Authors: Chen W, Chen R, He Q Abstract The abundance of neuroimaging data and rapid development of machine learning has made it possible to investigate brain activation patterns. However, causal evidence of brain area activation leading to a behavior is often left missing. Transcranial direct current stimulation (tDCS), which can temporarily alter brain cortical excitability and activity, is a noninvasive neurophysiological tool used to study causal relationships in the human brain. High-definition transcranial direct current stimulation (HD-tDCS) is a noninvasive brain ... read more
    Pubmed – tDCS and CognitionPublished on 2020-01-07
    3 months ago
  • Transcranial direct current stimulation in attention-deficit hyperactivity disorder: A meta-analysis of neuropsychological deficits.
    Related ArticlesTranscranial direct current stimulation in attention-deficit hyperactivity disorder: A meta-analysis of neuropsychological deficits. PLoS One. 2019;14(4):e0215095 Authors: Salehinejad MA, Wischnewski M, Nejati V, Vicario CM, Nitsche MA Abstract Transcranial direct current stimulation (tDCS) is a promising method for altering cortical excitability with clinical implications in neuropsychiatric diseases. Its application in neurodevelopmental disorders especially attention-deficit hyperactivity disorder (ADHD), is in early stage and promising but its effectiveness has not been systematically examined yet. We conducted a meta-analysis on the effectiveness of tDCS on the most studied neuropsychological symptoms of ADHD, which is the first reported meta-analysis of tDCS ... read more
    Pubmed – tDCS and CognitionPublished on 2020-01-07
    3 months ago
  • Inverse relationship between amplitude and latency of physiological mirror activity during repetitive isometric contractions.
    Related ArticlesInverse relationship between amplitude and latency of physiological mirror activity during repetitive isometric contractions. Neuroscience. 2019 05 15;406:300-313 Authors: Maudrich T, Kenville R, Nikulin VV, Maudrich D, Villringer A, Ragert P Abstract Mirror Activity (MA) is a phenomenon that is characterized by involuntarily occurring muscular activity in homologous contralateral limbs during unilateral movements. Even in neurologically healthy humans, MA of a small extent has been described, which does not directly lead to visible movements, but nonetheless, it is still detectable with surface electromyography (EMG) and therefore defined as physiological MA (pMA). The present study investigated latency- and ... read more
    Pubmed – tDCS and CognitionPublished on 2020-01-03
    3 months ago