Scientific Studies on tDCS and Learning

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Scientific Studies Related to tDCS and Learning

This collection of articles was sourced from PubMed.gov

As of Dec. 29th, we found 548 articles focusing on tDCS and Learning

  • Effects of Multiple Sessions of Cathodal Priming and Anodal HD-tDCS on Visuo Motor Task Plateau Learning and Retention.
    Related ArticlesEffects of Multiple Sessions of Cathodal Priming and Anodal HD-tDCS on Visuo Motor Task Plateau Learning and Retention. Brain Sci. 2020 Nov 19;10(11): Authors: Besson P, Muthalib M, De Vassoigne C, Rothwell J, Perrey S Abstract A single session of priming cathodal transcranial direct current stimulation (tDCS) prior to anodal tDCS (c-a-tDCS) allows cumulative effects on motor learning and retention. However, the impact of multiple sessions of c-a-tDCS priming on learning and retention remains unclear. Here, we tested whether multiple sessions of c-a-tDCS (over 3 consecutive days) applied over the left sensorimotor cortex can further enhance motor learning and ... read more
    2 days ago
  • Utilizing transcranial direct current stimulation to enhance laparoscopic technical skills training: A randomized controlled trial.
    Related ArticlesUtilizing transcranial direct current stimulation to enhance laparoscopic technical skills training: A randomized controlled trial. Brain Stimul. 2020 May - Jun;13(3):863-872 Authors: Cox ML, Deng ZD, Palmer H, Watts A, Beynel L, Young JR, Lisanby SH, Migaly J, Appelbaum LG Abstract BACKGROUND: Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique that delivers constant, low electrical current resulting in changes to cortical excitability. Prior work suggests it may enhance motor learning giving it the potential to augment surgical technical skill acquisition. OBJECTIVES: The aim of this study was to test the efficacy of tDCS, coupled ... read more
    3 days ago
  • Determination of anodal tDCS duration threshold for reversal of corticospinal excitability: An investigation for induction of counter-regulatory mechanisms.
    Related ArticlesDetermination of anodal tDCS duration threshold for reversal of corticospinal excitability: An investigation for induction of counter-regulatory mechanisms. Brain Stimul. 2020 May - Jun;13(3):832-839 Authors: Hassanzahraee M, Nitsche MA, Zoghi M, Jaberzadeh S Abstract BACKGROUND: Transcranial direct current stimulation (tDCS) is used to induce neuroplasticity in the human brain. Within certain limits of stimulation duration, anodal tDCS (a-tDCS) over the primary motor cortex induces long term potentiation- (LTP) like plasticity. A reversal of the direction of plasticity has however been described with prolonged a-tDCS protocols. OBJECTIVE: We aimed to systematically investigate the intervention duration threshold for reversal ... read more
    3 days ago
  • Effects of tDCS on Tactile Perception Depend on Tactile Expertise in Both Musicians and Non-Musicians.
    Related ArticlesEffects of tDCS on Tactile Perception Depend on Tactile Expertise in Both Musicians and Non-Musicians. Brain Sci. 2020 Nov 12;10(11): Authors: Godde B, Dadashev L, Karim AA Abstract Brain plasticity in the somatosensory cortex and tactile performance can be facilitated by brain stimulation. Here, we investigated the effects of transcranial direct current stimulation (tDCS) on tactile perception in musicians and non-musicians to elucidate how tDCS-effects might depend on tactile expertise. On three separate days, 17 semi-professional musicians (e.g., piano or violin players) and 16 non-musicians aged 18-27 years received 15 min of 1 mA anodal (a-tDCS), cathodal (c-tDCS) or ... read more
    1 week ago
  • Age as a Mediator of tDCS Effects on Pain: An Integrative Systematic Review and Meta-Analysis.
    Related ArticlesAge as a Mediator of tDCS Effects on Pain: An Integrative Systematic Review and Meta-Analysis. Front Hum Neurosci. 2020;14:568306 Authors: Saldanha JS, Zortea M, Torres ILDS, Fregni F, Caumo W Abstract Introduction: The transcranial direct current stimulation (tDCS) is a neuromodulatory technique with the potential to decrease pain scores and to improve chronic pain treatment. Although age is an essential factor that might impact the tDCS effect, most studies are solely conducted in adults. Therefore, the age limitation presents a critical research gap in this field and can be shown by only a handful of studies that ... read more
    1 week ago
  • Transcranial direct-current stimulation combined with attention increases cortical excitability and improves motor learning in healthy volunteers.
    Related ArticlesTranscranial direct-current stimulation combined with attention increases cortical excitability and improves motor learning in healthy volunteers. J Neuroeng Rehabil. 2020 02 19;17(1):23 Authors: Yamaguchi T, Moriya K, Tanabe S, Kondo K, Otaka Y, Tanaka S Abstract BACKGROUND: Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique that has the potential to induce motor cortical plasticity in humans. It is well known that motor cortical plasticity plays an essential role in motor learning and recovery in patients with stroke and neurodegenerative disorders. However, it remains unclear how cognitive function influences motor cortical plasticity induced by tDCS. ... read more
    2 weeks ago
  • Early stimulation of the left posterior parietal cortex promotes representation change in problem solving.
    Related ArticlesEarly stimulation of the left posterior parietal cortex promotes representation change in problem solving. Sci Rep. 2019 11 11;9(1):16523 Authors: Debarnot U, Schlatter S, Monteil J, Guillot A Abstract When you suddenly understand how to solve a problem through an original and efficient strategy, you experience the so-called "Eureka" effect. The appearance of insight usually occurs after setting the problem aside for a brief period of time (i.e. incubation), thereby promoting unconscious and novel associations on problem-related representations leading to a new and efficient solving strategy. The left posterior parietal cortex (lPPC) has been showed to ... read more
    3 weeks ago
  • Effect of single-session transcranial direct current stimulation on cognition in Parkinson’s disease.
    Related ArticlesEffect of single-session transcranial direct current stimulation on cognition in Parkinson's disease. CNS Neurosci Ther. 2019 11;25(11):1237-1243 Authors: Lau CI, Liu MN, Chang KC, Chang A, Bai CH, Tseng CS, Walsh V, Wang HC Abstract AIMS: Nonmotor symptoms (NMS) such as cognitive impairment and impulse-control disorders in Parkinson's disease (PD) remain a therapeutic challenge. Transcranial direct current stimulation (tDCS) has emerged as a promising alternative, although its immediate effects on NMS have been less well defined. In this randomized, sham-controlled, crossover study, we aimed to explore the single-session tDCS effects on cognitive performance in PD. METHODS: Ten ... read more
    4 weeks ago
  • Efficacy of single-session transcranial direct current stimulation on addiction-related inhibitory control and craving: a randomized trial in males with Internet gaming disorder.
    Related ArticlesEfficacy of single-session transcranial direct current stimulation on addiction-related inhibitory control and craving: a randomized trial in males with Internet gaming disorder. J Psychiatry Neurosci. 2020 Oct 29;46(1):190137 Authors: Wu LL, Potenza MN, Zhou N, Kober H, Shi XH, Yip SW, Xu JH, Zhu L, Wang R, Liu GQ, Zhang JT Abstract BACKGROUND: Transcranial direct current stimulation (tDCS) of the dorsolateral prefrontal cortex (dlPFC) may reduce substance use and other addictive behaviours. However, the cognitive mechanisms that underpin such effects remain unclear. Impaired inhibitory control linked to hypoactivation of the prefrontal cortex may allow craving-related motivations to lead to ... read more
    4 weeks ago
  • Anhedonia across borders: Transdiagnostic relevance of reward dysfunction for noninvasive brain stimulation endophenotypes.
    Related ArticlesAnhedonia across borders: Transdiagnostic relevance of reward dysfunction for noninvasive brain stimulation endophenotypes. CNS Neurosci Ther. 2019 11;25(11):1229-1236 Authors: Spano MC, Lorusso M, Pettorruso M, Zoratto F, Di Giuda D, Martinotti G, di Giannantonio M Abstract INTRODUCTION: Anhedonia is a transdiagnostic psychopathological dimension, consisting in the impaired ability to experience pleasure. In order to further our understanding of its neural correlates and to explore its potential relevance as a predictor of treatment response, in this article we systematically reviewed studies involving anhedonia and neuromodulation interventions, across different disorders. METHODS: We included seven studies fulfilling inclusion/exclusion criteria and ... read more
    4 weeks ago
  • Appraising the effectiveness of electrical and magnetic brain stimulation techniques in acute major depressive episodes: an umbrella review of meta-analyses of randomized controlled trials.
    Related ArticlesAppraising the effectiveness of electrical and magnetic brain stimulation techniques in acute major depressive episodes: an umbrella review of meta-analyses of randomized controlled trials. Braz J Psychiatry. 2020 Oct 23;: Authors: Razza LB, Afonso Dos Santos L, Borrione L, Bellini H, Branco LC, Cretaz E, Duarte D, Ferrão Y, Galhardoni R, Quevedo J, Simis M, Fregni F, Correll CU, Padberg F, Trevizol A, Daskalakis ZJ, Carvalho AF, Solmi M, Brunoni AR Abstract Electrical and magnetic brain stimulation techniques present distinct mechanisms and efficacy in the acute treatment of depression. This was an umbrella review of meta-analyses of randomized ... read more
    4 weeks ago
  • Simulation Analyses of tDCS Montages for the Investigation of Dorsal and Ventral Pathways.
    Related ArticlesSimulation Analyses of tDCS Montages for the Investigation of Dorsal and Ventral Pathways. Sci Rep. 2019 08 21;9(1):12178 Authors: Bhattacharjee S, Kashyap R, Rapp B, Oishi K, Desmond JE, Chen SHA Abstract Modulating higher cognitive functions like reading with transcranial direct current stimulation (tDCS) can be challenging as reading involves regions in the dorsal and ventral cortical areas that lie in close proximity. If the two pathways are stimulated simultaneously, the function of dorsal pathway (predominantly used for graphophonological conversion) might interfere with the function of the ventral pathway (used for semantics), and vice-versa. To achieve ... read more
    1 month ago
  • Theta band high definition transcranial alternating current stimulation, but not transcranial direct current stimulation, improves associative memory performance.
    Related ArticlesTheta band high definition transcranial alternating current stimulation, but not transcranial direct current stimulation, improves associative memory performance. Sci Rep. 2019 06 12;9(1):8562 Authors: Lang S, Gan LS, Alrazi T, Monchi O Abstract Associative memory (AM) deficits are common in neurodegenerative disease and novel therapies aimed at improving these faculties are needed. Theta band oscillations within AM networks have been shown to be important for successful memory encoding and modulating these rhythms represents a promising strategy for cognitive enhancement. Transcranial alternating current stimulation (TACS) has been hypothesized to entrain and increase power of endogenous brain rhythms. ... read more
    1 month ago
  • Effects of anodal transcranial direct current stimulation on cognitive dysfunction in patients with progressive supranuclear palsy.
    Related ArticlesEffects of anodal transcranial direct current stimulation on cognitive dysfunction in patients with progressive supranuclear palsy. Psychiatriki. 2019 Oct-Dec;30(4):320-328 Authors: Alexoudi A, Patrikelis P, Deftereos S, Fasilis T, Karakalos D, Verentzioti A, Korfias S, Sakas D, Gatzonis S Abstract Progressive supranuclear palsy (PSP) is a tauopathy characterized by motor, neurobehavioral and disabling brainstem deficits. No disease-modifying therapeutic options exist. The therapeutic potential of transcranial direct current stimulation (tDCS) has been highlighted in studies on patients with other neurodegenerative diseases. Therefore, by drawing upon the limited tDCS literature on PSP, we conducted a pilot study in order to evaluate the ... read more
    2 months ago
  • Randomized controlled trial of TDCS on cognition in 201 seniors with mild neurocognitive disorder.
    Related ArticlesRandomized controlled trial of TDCS on cognition in 201 seniors with mild neurocognitive disorder. Ann Clin Transl Neurol. 2019 10;6(10):1938-1948 Authors: Lu H, Chan SSM, Chan WC, Lin C, Cheng CPW, Linda Chiu Wa L Abstract OBJECTIVE: To examine the efficacy and safety of combined transcranial direct current stimulation (tDCS) and working memory training (WMT) in enhancing the cognitive functions for individuals with mild neurocognitive disorder due to AD (NCD-AD). METHODS: In this double-blind, sham-controlled randomized clinical trial (RCT), 201 patients with NCD-AD were randomly assigned for a 4-week intervention of either a combination of tDCS and ... read more
    3 months ago
  • Precision non-implantable neuromodulation therapies: a perspective for the depressed brain.
    Related ArticlesPrecision non-implantable neuromodulation therapies: a perspective for the depressed brain. Braz J Psychiatry. 2020 08;42(4):403-419 Authors: Borrione L, Bellini H, Razza LB, Avila AG, Baeken C, Brem AK, Busatto G, Carvalho AF, Chekroud A, Daskalakis ZJ, Deng ZD, Downar J, Gattaz W, Loo C, Lotufo PA, Martin MDGM, McClintock SM, O'Shea J, Padberg F, Passos IC, Salum GA, Vanderhasselt MA, Fraguas R, Benseñor I, Valiengo L, Brunoni AR Abstract Current first-line treatments for major depressive disorder (MDD) include pharmacotherapy and cognitive-behavioral therapy. However, one-third of depressed patients do not achieve remission after multiple medication trials, and psychotherapy ... read more
    3 months ago
  • No effects of cerebellar transcranial direct current stimulation on force field and visuomotor reach adaptation in young and healthy subjects.
    Related ArticlesNo effects of cerebellar transcranial direct current stimulation on force field and visuomotor reach adaptation in young and healthy subjects. J Neurophysiol. 2019 06 01;121(6):2112-2125 Authors: Mamlins A, Hulst T, Donchin O, Timmann D, Claassen J Abstract Previous studies have shown that cerebellar transcranial direct current stimulation (tDCS) leads to faster adaptation of arm reaching movements to visuomotor rotation and force field perturbations in healthy subjects. The first aim of the present study was to confirm a stimulation-dependent effect on motor adaptation. Second, we investigated whether tDCS effects differ depending on onset, that is, before or at the ... read more
    3 months ago
  • Transcranial direct current stimulation facilitates category learning.
    Related ArticlesTranscranial direct current stimulation facilitates category learning. Brain Stimul. 2020 Mar - Apr;13(2):393-400 Authors: Gibson BC, Mullins TS, Heinrich MD, Witkiewitz K, Yu AB, Hansberger JT, Clark VP Abstract BACKGROUND: After two decades of transcranial direct current stimulation (tDCS) research, it is still unclear which applications benefit most from which tDCS protocols. One prospect is the acceleration of learning, where previous work has demonstrated that anodal tDCS applied to the right ventrolateral prefrontal cortex (rVLPFC) is capable of doubling the rate of learning in a visual camouflaged threat detection and category learning task. GOALS: Questions remain as ... read more
    3 months ago
  • Anodal Transcranial Direct Current Stimulation to the Left Rostrolateral Prefrontal Cortex Selectively Improves Source Memory Retrieval.
    Related ArticlesAnodal Transcranial Direct Current Stimulation to the Left Rostrolateral Prefrontal Cortex Selectively Improves Source Memory Retrieval. J Cogn Neurosci. 2019 09;31(9):1380-1391 Authors: Westphal AJ, Chow TE, Ngoy C, Zuo X, Liao V, Storozuk LA, Peters MAK, Wu AD, Rissman J Abstract Functional neuroimaging studies have consistently implicated the left rostrolateral prefrontal cortex (RLPFC) as playing a crucial role in the cognitive operations supporting episodic memory and analogical reasoning. However, the degree to which the left RLPFC causally contributes to these processes remains underspecified. We aimed to assess whether targeted anodal stimulation-thought to boost cortical excitability-of the left RLPFC with ... read more
    3 months ago
  • Direct current stimulation boosts hebbian plasticity in vitro.
    Related ArticlesDirect current stimulation boosts hebbian plasticity in vitro. Brain Stimul. 2020 Mar - Apr;13(2):287-301 Authors: Kronberg G, Rahman A, Sharma M, Bikson M, Parra LC Abstract BACKGROUND: There is evidence that transcranial direct current stimulation (tDCS) can improve learning performance. Arguably, this effect is related to long term potentiation (LTP), but the precise biophysical mechanisms remain unknown. HYPOTHESIS: We propose that direct current stimulation (DCS) causes small changes in postsynaptic membrane potential during ongoing endogenous synaptic activity. The altered voltage dynamics in the postsynaptic neuron then modify synaptic strength via the machinery of endogenous voltage-dependent Hebbian plasticity. This ... read more
    4 months ago
  • Anodal Transcranial Direct Current Stimulation Can Improve Spatial Learning and Memory and Attenuate Aβ42 Burden at the Early Stage of Alzheimer’s Disease in APP/PS1 Transgenic Mice.
    Related ArticlesAnodal Transcranial Direct Current Stimulation Can Improve Spatial Learning and Memory and Attenuate Aβ42 Burden at the Early Stage of Alzheimer's Disease in APP/PS1 Transgenic Mice. Front Aging Neurosci. 2020;12:134 Authors: Luo Y, Yang W, Li N, Yang X, Zhu B, Wang C, Hou W, Wang X, Wen H, Tian X Abstract Alzheimer's disease (AD) is an irreversible progressive neurodegenerative disease. Intervention in the early stage of AD is a new path for AD treatment that is being explored. The behavioral and pathological effects of anodal transcranial direct current stimulation (AtDCS) at the early stage of AD ... read more
    5 months ago
  • Beyond the target area: an integrative view of tDCS-induced motor cortex modulation in patients and athletes.
    Related ArticlesBeyond the target area: an integrative view of tDCS-induced motor cortex modulation in patients and athletes. J Neuroeng Rehabil. 2019 11 15;16(1):141 Authors: Morya E, Monte-Silva K, Bikson M, Esmaeilpour Z, Biazoli CE, Fonseca A, Bocci T, Farzan F, Chatterjee R, Hausdorff JM, da Silva Machado DG, Brunoni AR, Mezger E, Moscaleski LA, Pegado R, Sato JR, Caetano MS, Sá KN, Tanaka C, Li LM, Baptista AF, Okano AH Abstract Transcranial Direct Current Stimulation (tDCS) is a non-invasive technique used to modulate neural tissue. Neuromodulation apparently improves cognitive functions in several neurologic diseases treatment and sports performance. ... read more
    6 months ago
  • Direct current stimulation-induced synaptic plasticity in the sensorimotor cortex: structure follows function.
    Related ArticlesDirect current stimulation-induced synaptic plasticity in the sensorimotor cortex: structure follows function. Brain Stimul. 2020 Jan - Feb;13(1):80-88 Authors: Gellner AK, Reis J, Holtick C, Schubert C, Fritsch B Abstract BACKGROUND: Non-invasive direct current stimulation (DCS) of the brain induces functional plasticity in vitro and facilitates motor learning across species. The effect of DCS on structural synaptic plasticity is currently unknown. OBJECTIVE: This study addresses the effects and the underlying mechanisms of anodal DCS on structural plasticity and morphology of dendritic spines in the sensorimotor cortex (M1/S1). METHODS: A DCS electrode setup was combined with a chronic cranial ... read more
    6 months ago
  • Anodal tDCS over the right parietal but not frontal cortex enhances the ability to overcome task set inhibition during task switching.
    Related ArticlesAnodal tDCS over the right parietal but not frontal cortex enhances the ability to overcome task set inhibition during task switching. PLoS One. 2020;15(2):e0228541 Authors: Sdoia S, Zivi P, Ferlazzo F Abstract Switching between tasks requires individuals to inhibit mental representations of the previous task demands and to activate representations of the new task demands. The inhibition of the executed task remains active for a while so that when the inhibited task set must be re-activated shortly after, the need to overcome residual task set inhibition leads to behavioral costs. In a sham-controlled balanced-order within-subjects experimental design ... read more
    7 months ago
  • Anodal transcranial direct current stimulation reduces collinear lateral inhibition in normal peripheral vision.
    Related ArticlesAnodal transcranial direct current stimulation reduces collinear lateral inhibition in normal peripheral vision. PLoS One. 2020;15(5):e0232276 Authors: Raveendran RN, Tsang K, Tiwana D, Chow A, Thompson B Abstract Collinear flanking stimuli can reduce the detectability of a Gabor target presented in peripheral vision. This phenomenon is called collinear lateral inhibition and it may contribute to crowding in peripheral vision. Perceptual learning can reduce collinear lateral inhibition in peripheral vision, however intensive training is required. Our aim was to assess whether modulation of collinear lateral inhibition can be achieved within a short time-frame using a single 20-minute session of ... read more
    7 months ago