Published Research Studies on tDCS

Published Research Studies on tDCS

The scientific and academic research communities have been studying Transcranial Direct Current Stimulation (tDCS) for decades, with interest in the topic exploding over the last 10-15 years. The number of scientific studies conducted per year has increased every year since 2006. In 2007, 2008 and 2011, the number of published studies on tDCS doubled that of the previous year.

As of May 2019, there are over 4,200 research papers on tDCS available through PubMed alone! Below you will find a collection of the latest studies recently published on tDCS. Each study includes information on where the paper was published along with publication date, contributing authors, and an abstract or summary of the findings.

 

  • Does transcranial direct current stimulation improve functional locomotion in people with Parkinson’s disease? A systematic review and meta-analysis.
    Does transcranial direct current stimulation improve functional locomotion in people with Parkinson's disease? A systematic review and meta-analysis. J Neuroeng Rehabil. 2019 Jul 08;16(1):84 Authors: Lee HK, Ahn SJ, Shin YM, Kang N, Cauraugh JH Abstract PURPOSE: The purpose of this meta-analysis was to investigate the treatment effects of transcranial direct current stimulation (tDCS) on functional locomotion in people with Parkinson's disease (PD). METHODS: A systematic literature search identified 18 qualified studies that used tDCS protocols as functional locomotion rehabilitation interventions for people with PD. All included studies used either a randomized control trial or crossover designs with a sham ... read more
    1 week ago
  • Transcranial direct current stimulation (tDCS) in elderly with mild cognitive impairment: A pilot study.
    Transcranial direct current stimulation (tDCS) in elderly with mild cognitive impairment: A pilot study. Dement Neuropsychol. 2019 Apr-Jun;13(2):187-195 Authors: Gomes MA, Akiba HT, Gomes JS, Trevizol AP, de Lacerda ALT, Dias ÁM Abstract Transcranial direct current stimulation (tDCS) is a non-invasive, painless and easy-to use-technology. It can be used in depression, schizophrenia and other neurological disorders. There are no studies about longer usage protocols regarding the ideal duration and weekly frequency of tDCS. Objective: to study the use of tDCS twice a week for longer periods to improve memory in elderly with MCI. Methods: a randomized double-blind controlled trial of ... read more
    1 week ago
  • Transcranial direct current stimulation (tDCS) effects on traumatic brain injury (TBI) recovery: A systematic review.
    Transcranial direct current stimulation (tDCS) effects on traumatic brain injury (TBI) recovery: A systematic review. Dement Neuropsychol. 2019 Apr-Jun;13(2):172-179 Authors: Zaninotto AL, El-Hagrassy MM, Green JR, Babo M, Paglioni VM, Benute GG, Paiva WS Abstract Traumatic brain injury (TBI) is a major cause of chronic disability. Less than a quarter of moderate and severe TBI patients improved in their cognition within 5 years. Non-invasive brain stimulation, including transcranial direct current stimulation (tDCS), may help neurorehabilitation by boosting adaptive neuroplasticity and reducing pathological sequelae following TBI. Methods: we searched MEDLINE/PubMed and Web of Science databases. We used Jadad scale to assess ... read more
    1 week ago
  • A single session of bihemispheric transcranial direct current stimulation does not improve quadriceps muscle spasticity in people with chronic stroke.
    A single session of bihemispheric transcranial direct current stimulation does not improve quadriceps muscle spasticity in people with chronic stroke. Brain Stimul. 2019 Jun 28;: Authors: Cattagni T, Geiger M, Supiot A, Zory R, Pradon D, Roche N PMID: 31285163 [PubMed - as supplied by publisher] ... read more
    1 week ago
  • Effect of multichannel transcranial direct current stimulation to reduce hypertonia in individuals with prolonged disorders of consciousness: a randomized controlled pilot study.
    Related ArticlesEffect of multichannel transcranial direct current stimulation to reduce hypertonia in individuals with prolonged disorders of consciousness: a randomized controlled pilot study. Ann Phys Rehabil Med. 2019 Jul 05;: Authors: Thibaut A, Piarulli A, Martens G, Chatelle C, Laureys S Abstract BACKGROUND: Spasticity management in severely brain-injured patients with disorders of consciousness (DOC) is a major challenge because it leads to complications and severe pain that can seriously affect quality of life. OBJECTIVES: We aimed to determine the feasibility of using transcranial direct current stimulations (tDCS) to reduce spasticity in chronic patients with DOC. METHODS: We enrolled 14 patients ... read more
    1 week ago
  • Brain Stimulation in Obsessive-Compulsive Disorder (OCD): A Systematic Review.
    Related ArticlesBrain Stimulation in Obsessive-Compulsive Disorder (OCD): A Systematic Review. Curr Neuropharmacol. 2019 04 09;: Authors: Rapinesi C, Kotzalidis GD, Ferracuti S, Sani G, Girardi P, Del Casale A Abstract BACKGROUND: Obsessive-compulsive disorder (OCD) is highly prevalent, severe, chronic, and disabling. There is need for alternative strategies for treatment-resistant OCD. OBJECTIVE: This review aims to assess the effect of brain stimulation techniques in OCD. METHOD: We included papers published in peer-reviewed journals dealing with brain stimulation techniques in OCD. We conducted treatment-specific searches for OCD (Technique AND ((randomized OR randomised) AND control* AND trial) AND (magnetic AND stimulation OR ... read more
    3 months ago
  • Effects of in-Scanner Bilateral Frontal tDCS on Functional Connectivity of the Working Memory Network in Older Adults.
    Related ArticlesEffects of in-Scanner Bilateral Frontal tDCS on Functional Connectivity of the Working Memory Network in Older Adults. Front Aging Neurosci. 2019;11:51 Authors: Nissim NR, O'Shea A, Indahlastari A, Telles R, Richards L, Porges E, Cohen R, Woods AJ Abstract Working memory is an executive memory process essential for everyday decision-making and problem solving that declines with advanced age. Transcranial direct current stimulation (tDCS) is a non-invasive form of brain stimulation that has demonstrated potential for improving working memory performance in older adults. However, the neural mechanisms underlying effects of tDCS on working memory are not well understood. ... read more
    3 months ago
  • Clinical improvement with intensive robot-assisted arm training in chronic stroke is unchanged by supplementary tDCS.
    Related ArticlesClinical improvement with intensive robot-assisted arm training in chronic stroke is unchanged by supplementary tDCS. Restor Neurol Neurosci. 2019;37(2):167-180 Authors: Edwards DJ, Cortes M, Rykman-Peltz A, Chang J, Elder J, Thickbroom G, Mariman JJ, Gerber LM, Oromendia C, Krebs HI, Fregni F, Volpe BT, Pascual-Leone A Abstract BACKGROUND: Intensive robot-assisted arm training in the chronic phase of stroke recovery can lead to clinical improvement. Combinatorial therapeutic approaches are sought to further optimize stroke recovery. Transcranial direct current stimulation (tDCS) is one candidate to combine with robotic training, as transient increases in excitability and improvements in motor behavior have ... read more
    3 months ago
  • Electromagnetic Brain Stimulation in Patients With Disorders of Consciousness.
    Related ArticlesElectromagnetic Brain Stimulation in Patients With Disorders of Consciousness. Front Neurosci. 2019;13:223 Authors: Bourdillon P, Hermann B, Sitt JD, Naccache L Abstract Severe brain injury is a common cause of coma. In some cases, despite vigilance improvement, disorders of consciousness (DoC) persist. Several states of impaired consciousness have been defined, according to whether the patient exhibits only reflexive behaviors as in the vegetative state/unresponsive wakefulness syndrome (VS/UWS) or purposeful behaviors distinct from reflexes as in the minimally conscious state (MCS). Recently, this clinical distinction has been enriched by electrophysiological and neuroimaging data resulting from a better understanding ... read more
    3 months ago
  • Effects of Transcranial Direct Current Stimulation of Primary Motor Cortex on Reaction Time and Tapping Performance: A Comparison Between Athletes and Non-athletes.
    Related ArticlesEffects of Transcranial Direct Current Stimulation of Primary Motor Cortex on Reaction Time and Tapping Performance: A Comparison Between Athletes and Non-athletes. Front Hum Neurosci. 2019;13:103 Authors: Seidel O, Ragert P Abstract Recent studies provided compelling evidence that physical activity leads to specific changes on a functional and structural level of brain organization. The observed neural adaptions are specific to the sport and manifested in those brain regions which are associated with neuronal processing of sport-specific skills. Techniques of non-invasive brain stimulation have been shown to induce neuroplastic changes and thereby also facilitate task performance. In the ... read more
    3 months ago
  • Cerebellar Theta Frequency Transcranial Pulsed Stimulation Increases Frontal Theta Oscillations in Patients with Schizophrenia.
    Related ArticlesCerebellar Theta Frequency Transcranial Pulsed Stimulation Increases Frontal Theta Oscillations in Patients with Schizophrenia. Cerebellum. 2019 Mar 01;: Authors: Singh A, Trapp NT, De Corte B, Cao S, Kingyon J, Boes AD, Parker KL Abstract Cognitive dysfunction is a pervasive and disabling aspect of schizophrenia without adequate treatments. A recognized correlate to cognitive dysfunction in schizophrenia is attenuated frontal theta oscillations. Neuromodulation to normalize these frontal rhythms represents a potential novel therapeutic strategy. Here, we evaluate whether noninvasive neuromodulation of the cerebellum in patients with schizophrenia can enhance frontal theta oscillations, with the future goal of targeting the ... read more
    5 months ago
  • The Effects of Transcranial Direct Current Stimulation (tDCS) on Working Memory Training in Healthy Young Adults.
    Related ArticlesThe Effects of Transcranial Direct Current Stimulation (tDCS) on Working Memory Training in Healthy Young Adults. Front Hum Neurosci. 2019;13:19 Authors: Ke Y, Wang N, Du J, Kong L, Liu S, Xu M, An X, Ming D Abstract Working memory (WM) is a fundamental cognitive ability to support complex thought, but it is limited in capacity. WM training has shown the potential benefit for those in need of a higher WM ability. Many studies have shown the potential of transcranial direct current stimulation (tDCS) to transiently enhance WM performance by delivering a low current to the brain ... read more
    5 months ago
  • Psychogenic non-epileptic seizures treated with guided transcranial direct current stimulation: A case report.
    Related ArticlesPsychogenic non-epileptic seizures treated with guided transcranial direct current stimulation: A case report. Brain Stimul. 2019 Jan 31;: Authors: Leroy A, Beigné M, Petyt G, Derambure P, Vaiva G, Amad A Abstract INTRODUCTION: Psychogenic non-epileptic seizures (PNES) are paroxysms of either altered subjective or objective manifestations that may mimic epileptic seizures (ES), without abnormal neuronal epileptiform activity. In this report, we present the case of a 39-year-old woman with PNES and functional movement disorders, who was successfully treated with neuro-guided transcranial direct current stimulation (tDCS). METHODS: We used a PET-guided tDCS approach, as a hypometabolism of the frontal ... read more
    5 months ago
  • Transcranial Direct Current Stimulation of motor cortex enhances running performance.
    Related ArticlesTranscranial Direct Current Stimulation of motor cortex enhances running performance. PLoS One. 2019;14(2):e0211902 Authors: Park SB, Sung DJ, Kim B, Kim S, Han JK Abstract Transcranial direct current stimulation (tDCS) is a technique used to modulate neuronal excitability through non-invasive brain stimulation that can enhance exercise performance. We hypothesize that tDCS would improve submaximal running time to exhaustion (TTE) and delay the increase in the rating of perceived exertion (RPE) over time. We also hypothesize that tDCS would not lead to difference in cardiorespiratory responses. We employed a randomized, single-blinded, and counterbalanced design in which 10 trained men participated. ... read more
    5 months ago
  • Neuromodulation Strategies in Post-Traumatic Stress Disorder: From Preclinical Models to Clinical Applications.
    Related ArticlesNeuromodulation Strategies in Post-Traumatic Stress Disorder: From Preclinical Models to Clinical Applications. Brain Sci. 2019 Feb 19;9(2): Authors: Gouveia FV, Gidyk DC, Giacobbe P, Ng E, Meng Y, Davidson B, Abrahao A, Lipsman N, Hamani C Abstract Post-traumatic stress disorder (PTSD) is an often debilitating disease with a lifetime prevalence rate between 5⁻8%. In war veterans, these numbers are even higher, reaching approximately 10% to 25%. Although most patients benefit from the use of medications and psychotherapy, approximately 20% to 30% do not have an adequate response to conventional treatments. Neuromodulation strategies have been investigated for various psychiatric disorders ... read more
    5 months ago
  • Cognitive effects of non-surgical brain stimulation for major depressive disorder: protocol for a systematic review and meta-analysis.
    Related ArticlesCognitive effects of non-surgical brain stimulation for major depressive disorder: protocol for a systematic review and meta-analysis. BMJ Open. 2019 Feb 19;9(2):e023796 Authors: Kiebs M, Hurlemann R, Mutz J Abstract INTRODUCTION: Non-surgical brain stimulation techniques may be considered as alternative or add-on treatments for patients with major depressive disorder who failed to respond to pharmacological interventions. Electroconvulsive therapy has been shown to be highly effective in reducing depressive symptoms but stakeholders remain concerned about adverse cognitive effects. Repetitive transcranial magnetic stimulation and transcranial direct current stimulation may be associated with more benign adverse effect profiles and may indeed ... read more
    5 months ago